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Gramicidin D
go.drugbank.com/drugs/DB00027ApprovedInvestigationalGramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus … Gramcidins are 15 residue peptides with alternating D and L amino acids, which assemble inside of the hydrophobic interior of the cellular lipid bilayer to form a β-helix.
Mixtures: Neomycin and Polymyxin B Sulfates and Gramicidin, Neomycin and Polymyxin B Sulfates and GramicidinCategories: Amino Acids, Peptides, and ProteinsAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigationalMerck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and … It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin.
Categories: Acetic Acid Derivatives and Related Substances, Antiinflammatory and Antirheumatic ProductsProducts: AZEAT 30MG, AZEAT 60MGThrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalOnce converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. … This thrombosis may result from the development of antibodies against bovine thrombin [FDA Label]. Bleeding may result from the development of antibodies against bovine factor V [FDA Label].
Mixtures: Tisseel Lyo - Pulver und Lösungsmittel für einen GewebekleberCategories: Enzymes and Coenzymes, Blood and Blood Forming OrgansNavepegritide
go.drugbank.com/drugs/DB17824ApprovedInvestigational[L56065] Navepegritide was approved by the US FDA in February 2026 for use in patients 2 years of age and older with achondroplasia with open epiphyses.[L56058,L56065] … Achondroplasia, the most prevalent skeletal dysplasia, is caused by a gain-of-function variant in the fibroblast growth factor receptor 3 (FGFR3), which leads to overactive downstream signaling that inhibits
Categories: Amino Acids, Peptides, and ProteinsChills occurring with fever
go.drugbank.com/conditions/DBCOND0097433Drugs: GuaifenesinSynonyms: Chills and fever, Chills and fever (finding)Myxedema coma
go.drugbank.com/conditions/DBCOND0020856Synonyms: Hypothyroidism - congenital and acquired (& [cretinism] or [myxoedema])Sonesitatug Vedotin
go.drugbank.com/drugs/DB18619InvestigationalCMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Synonyms: an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payloadSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalSerplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.
Categories: Antineoplastic and Immunomodulating Agents, Monoclonal antibodies and antibody drug conjugatesTelotristat ethyl
go.drugbank.com/drugs/DB12095Approved[A252947] The most common peptides and amines secreted by NET are histamines, tachykinins, kallikrein, and serotonin. … [A252937] Serotonin is metabolized in the urinary metabolite 5-hydroxy indole acetic acid (u5-HIAA), and high levels of u5-HIAA is associated with poor survival outcome in patients with NET.
KITE-222
go.drugbank.com/drugs/DB17195InvestigationalSynonyms: An autologous chimeric antigen receptor (CAR) T-cell therapy engineered to express an antibody-derived single-chain variable fragment that recognizes C-type lectin-like molecule-1 (CLL-1)