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Bamlanivimab
go.drugbank.com/drugs/DB15718ApprovedInvestigationalfor progressing to severe COVID-19:[L40179] this EUA later expanded in December 2021 to include all younger children at high risk, including newborns. … [L40174] The EUA currently allows bamlanivimab and etesevimab for post-exposure prophylaxis of COVID-19 in adults and children.[L40179]
Categories: Experimental Unapproved Treatments for COVID-19Clopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigational[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and … in recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and
Mixtures: CO-DEGREGANLutetium Lu-177 vipivotide tetraxetan
go.drugbank.com/drugs/DB16778ApprovedInvestigationalIt consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. … [L41290] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended lutetium Lu-177 vipivotide tetraxetan be granted marketing authorization for the treatment of prostate
Categories: Compounds used in a research, industrial, or household settingAllergic Rhinitis (AR)
go.drugbank.com/conditions/DBCOND0053380Drugs: Ambrosia artemisiifolia pollen · Amidephrine · Azelastine · Brompheniramine · Budesonide · Carbinoxamine +34 moreSynonyms: Allergic rhinitis due to allergenCentral Diabetes Insipidus
go.drugbank.com/conditions/DBCOND0051168Drugs: DesmopressinSynonyms: Diabetes insipidus secondary to vasopressin deficiencyInfections
go.drugbank.com/conditions/DBCOND0024541Drugs: Acetic acid · Ampicillin · Bacitracin · Benzamidine · Calcium hypochlorite · Chlorhexidine +18 moreSynonyms: Disease due to infectionEstetrol
go.drugbank.com/drugs/DB12235ApprovedInvestigational[L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. … [L33179] In Canada, Nextstellis was approved for use in March 2021; it was developed by Mithra and is marketed by Searchlight Pharma.[L33209]
Categories: Hormonal Contraceptives for Systemic UseBaricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018. … [A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe.
Categories: Experimental Unapproved Treatments for COVID-19Dextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedWhen labelled with technetium Tc99m, dextran 75 is intravenously administered as an imaging agent to detect and diagnose conditions in the vascular compartment such as pericardial effusion or ventricular … [A32011] Many bacteria, like _Leuconostoc_, can synthesize dextran from sucrose, and this activity is used commercially to obtain dextran.
Mixtures: Visine for Red Eye Cool, Visine for Red Eye WorkplaceCategories: Compounds used in a research, industrial, or household settingReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalBy targeting the IL-5 and disrupting its signalling pathways, reslizumab aims to inhibit eosinophil maturation and promote programmed cell death [A31578]. … In four double-blind, randomized, placebo‑controlled trials in patients with severe asthma on currently available therapies, patients receiving reslizumab had fewer asthma attacks, and a longer time to
Categories: Drugs for Obstructive Airway Diseases