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Tradipitant
go.drugbank.com/drugs/DB12580ApprovedInvestigational[A275353] Approved by the FDA on December 30, 2025, tradipitant is indicated for the prevention of vomiting induced by motion. … [L54903] NK-1 receptors are expressed in the brainstem and nucleus tractus solitarius, which receives emetogenic signals from various stimuli including dizziness and vertigo.
Remestemcel-L
go.drugbank.com/drugs/DB13973ApprovedInvestigationalWithdrawn[L11022] Remestemcel-L was later approved by the FDA on December 18, 2024. … [L52008] aGvHD is a T-cell mediated disease that occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues [A31822] developed by 30-80%
Teclistamab
go.drugbank.com/drugs/DB16655ApprovedInvestigational[L43612] Teclistamab was later granted accelerated approval by the FDA on October 25, 2022.[L43617] … [A253587] Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug to recruit CD3-expressing T cells to BCMA-expressing
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsDiabetic Neuropathies
go.drugbank.com/conditions/DBCOND0028190Drugs: Amitriptyline · Botulinum toxin type A · Citalopram · Cyanocobalamin · Desipramine · Lipoic acid +1 moreSynonyms: Neuropathy co-occurrent and due to diabetes mellitusVitamin B1 deficiency
go.drugbank.com/conditions/DBCOND0015755Synonyms: (Thiamine and niacin deficiency states) or (vitamin B1 deficiency)Atoltivimab
go.drugbank.com/drugs/DB15898ApprovedInvestigationalINMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320] … [A221825] Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid development, low toxicity, and high
Categories: Amino Acids, Peptides, and ProteinsAdapalene
go.drugbank.com/drugs/DB00210ApprovedInvestigational[A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. … [A193518] Adapalene has similar efficacy but a superior safety profile compared to tretinoin.
Mixtures: Adapalene and Benzoyl Peroxide, ADAPALENE and BENZOYL PEROXIDECategories: Skin and Mucous Membrane AgentsTedizolid phosphate
go.drugbank.com/drugs/DB09042Approved[L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®). … Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) and is generally more effective and more tolerable than [linezolid].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCoral snake (micrurus fulvius) immune globulin antivenin (equine)
go.drugbank.com/drugs/DB13883ApprovedIt is intravenously administered so that the antivenin binds to and neutralizes coral snake venom. … The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by fractionating blood from healthy horses that have been immunized with eastern coral snake (Micrurus
Formestane
go.drugbank.com/drugs/DB08905ApprovedWithdrawnFormestane has poor oral bioavailability, and thus must be administered fortnightly (bi-weekly) by intramuscular injection. … Some clinical data has suggested that the clinically recommended dose of 250mg was too low.
Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related Agents