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Octocrylene
go.drugbank.com/drugs/DB09535Approved10 or 12 percent. … Because of its effectiveness, the chemical has been approved across the globe for use in cosmetics and skin care products, but the concentrations of this ingredient are usually limited to no more than
Mixtures: Ambient Lip Shield Stick SPF 45, Sei Bella Daytime DeliverySodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnGold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Products: MIOCRIN 50 MG, MYOCRISIN INJECTION 20 MG (4% W/V)Paxalisib
go.drugbank.com/drugs/DB15186InvestigationalGDC-0084 is under investigation in clinical trial NCT03696355 (Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas).
Synonyms: 5-(6,6-dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amineCategories: Heterocyclic Compounds, 1-RingTranylcypromine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126672Drug actionTranylcypromine is a non-hydrazine monoamine oxidase inhibitor belonging to the class of antidepressants called MAOIs. This drug is indicated in the treatment of major depression, dysthymic disorder, and atypical depression. It also is u...
Enzymes: Amine oxidase [flavin-containing] A, Synaptic vesicular amine transporterPhenelzine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126682Drug actionPhenelzine, also known as Nardil, is a monoamine oxidase inhibitor (MAOIs). This drug is used as an antidepressant and it is also effective in the treatment of panic disorder and social anxiety disorder. The monoamine oxidase is an enzym...
Enzymes: Amine oxidase [flavin-containing] A, Synaptic vesicular amine transporterMinaprine Amine oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126684Drug actionFurthermore, minaprine also acts as a reversible inhibitor of the amine oxidase [flavin-containing] A enzyme.
Enzymes: Amine oxidase [flavin-containing] A, Synaptic vesicular amine transporterMoclobemide Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126685Drug actionMoclobemide is a reversible monoamine oxidase inhibitor (MAOIs) selective for the isoform A (RIMA). This molecule is indicated in the treatment of major depressive disorder (MDD) and bipolar disorder. he monoamine oxidase is an enzyme th...
Enzymes: Amine oxidase [flavin-containing] A, Synaptic vesicular amine transporterPargyline Amine Oxidase Serotonin Antidepressant Action Pathway
smpdb.ca/view/SMP0126766Drug actionPargyline is a monoamine oxidase B inhibitor (MAOI). This drug has antihypertensive properties and is, thus, indicated in treating moderate to severe hypertension. Pargyline inhibits the breakdown of monoamine neurotransmitters, leading ...
Enzymes: Amine oxidase [flavin-containing] B, Synaptic vesicular amine transporterRotigotine
go.drugbank.com/drugs/DB05271ApprovedInvestigationalIt was approved by the European Medicines Agency in 2006 and by the FDA in 2007. … However, all Neupro patches in the United States and some of Europe were recalled in 2008 due to delivery mechanism issues. Rotigotine has been authorized as a treatment for RLS since August 2008.
Categories: Heterocyclic Compounds, 1-RingSynonyms: (6S)-6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenolOsimertinib
go.drugbank.com/drugs/DB09330ApprovedInvestigationalApproximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs due to the presence of specific activating EGFR mutations within the tumour cells. … Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.
Synonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamideCategories: Heterocyclic Compounds, 1-Ring