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Oxacillin
go.drugbank.com/drugs/DB00713ApprovedInvestigationalAn antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid, (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidGemifloxacin
go.drugbank.com/drugs/DB01155ApprovedInvestigationalGemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. … Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingProducts: ONFACT 320 MG FİLM TABLET, 5 ADET, ONFACT 320 MG FİLM TABLET, 7 ADETAxitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigationalAxitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). … [L6676] Axitinib is an indazole derivative.[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide, AR-14034Bromazepam
go.drugbank.com/drugs/DB01558ApprovedIllicitIt is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: BROMAZEPAM AL 6, BROMAZEPAM 6 1A PHARMAMethylmalonic aciduria type A protein, mitochondrial
go.drugbank.com/bio_entities/BE0000320TargetHumansPlays a dual role as both a protectase and a reactivase for MMUT (PubMed:21138732, PubMed:28943303). … Functions as a G protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) (PubMed:20876572, PubMed:28497574).
Polypeptides: Methylmalonic aciduria type A protein, mitochondrialRibosomal small subunit pseudouridine synthase A
go.drugbank.com/bio_entities/BE0002034TargetEscherichia coli (strain K12)Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase APeroxisomal acyl-coenzyme A oxidase 1
go.drugbank.com/bio_entities/BE0004135TargetEnzymeHumansMay play a role in peroxisomal beta-oxidation step in polyunsaturated fatty acids (PUFAs) biosynthesis. … Catalyzes the desaturation of fatty acyl-CoAs that have a saturated bond between C2 and C3 (2,3-saturated acyl-CoA) to 2-trans-enoyl-CoAs ((2E)-enoyl-CoAs), and donates electrons directly to molecular
Polypeptides: Peroxisomal acyl-coenzyme A oxidase 1GABA(A) Receptor Benzodiazepine Binding Site
go.drugbank.com/bio_entities/BE0008668TargetHumansGABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit … GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit
Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activityMHC class I HLA-A protein
go.drugbank.com/bio_entities/BE0010186TargetHumansPolypeptides: MHC class I HLA-A proteinSynonyms: HLA-AHepatitis A virus cellular receptor 2
go.drugbank.com/bio_entities/BE0010551TargetHumansExpressed on natural killer (NK) cells and acts as a coreceptor to enhance IFN-gamma production in response to LGALS9 (PubMed:22323453).
Polypeptides: Hepatitis A virus cellular receptor 2