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Berberine
go.drugbank.com/drugs/DB04115ApprovedInvestigationalWithdrawnIt is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
HLX70
go.drugbank.com/drugs/DB16509InvestigationalHLX70, a recombinant humanized anti-S protein monoclonal antibody intended for intravenous infusion, was under investigation in clinical trials NCT05429385 and NCT04561076 to evaluate its safety and pharmacokinetics
Categories: Experimental Unapproved Treatments for COVID-19Pramlintide
go.drugbank.com/drugs/DB01278ApprovedInvestigationalPramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals.
NRP409
go.drugbank.com/drugs/DB05235ExperimentalNRP409 is a triiodothyronine (T3) hormone, being investigated by New River Pharmaceuticals as a treatment for patients with primary hypothyroidism.
ISIS 113715
go.drugbank.com/drugs/DB05506InvestigationalISIS 113715 is our second-generation antisense inhibitor of protein tyrosine phosphatase 1b, or PTP‑1b, for the treatment of type 2 diabetes.
Creatine
go.drugbank.com/drugs/DB00148ApprovedInvestigationalNutraceuticalAn amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Influenza A virus A/Hong Kong/2671/2019 IVR-208 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15704ApprovedInvestigationalA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposin...
Mixtures: Vaxigrip Tetra, Suspension for Injection in Pre-filled SyringeNitroxoline
go.drugbank.com/drugs/DB01422ExperimentalNitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a hydroxyquinoline derivative unrelated to other classes of drugs. Nitrox...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAprocitentan
go.drugbank.com/drugs/DB15059ApprovedInvestigationalEndothelin receptor antagonism provides a novel therapeutic pathway for the management of patients with resistant hypertension. … Aprocitentan is a dual antagonist of endothelin receptors A and B used for treatment-resistant hypertension. It is the active metabolite of [macitentan].
Ambroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalAmbroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several p...
Categories: Adrenergics for Systemic Use, Drugs for Obstructive Airway Diseases