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Aldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalAldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. … This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon
Synonyms: Interleukin-2(2-133),125-ser, 125-L-Serine-2-133-interleukin 2Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsEzogabine
go.drugbank.com/drugs/DB04953ApprovedWithdrawnIt is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures … Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine.
Synonyms: N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester, ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamateParomomycin
go.drugbank.com/drugs/DB01421ApprovedInvestigationalAn oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Synonyms: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, Neomycin EProducts: GABROSIDIN 0.5 G ENJEKTABL FLAKON, 1 ADETButoconazole
go.drugbank.com/drugs/DB00639ApprovedButoconazole is an imidazole antifungal used in gynecology.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[4-(4-Chloro-phenyl)-2-(2,6-dichloro-phenylsulfanyl)-butyl]-1H-imidazoleMaxy-G34
go.drugbank.com/drugs/DB05718Investigational, while Neulasta has a single 20 Kd PEG group attached at the N terminal end of the wild type G-CSF protein. … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF).
Categories: Compounds used in a research, industrial, or household settingNitroxoline
go.drugbank.com/drugs/DB01422ExperimentalIt is a hydroxyquinoline derivative unrelated to other classes of drugs.[A179251] Nitroxoline is active against bacterial gyrases. … Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-Nitro-8-quinolinol, 5-Nitro-8-oxyquinolineToremifene
go.drugbank.com/drugs/DB00539ApprovedInvestigationalToremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to treat estrogen receptor positive breast cancer.
Mixtures: FLOBACT - D, FLOBACT - DCategories: P-glycoprotein inhibitors, P-glycoprotein substratesATP
go.drugbank.com/drugs/DB00171InvestigationalNutraceuticalAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Categories: Heterocyclic Compounds, 2-RingSynonyms: Adenosine 5'-triphosphate, Adenosine-5'-triphosphateRidogrel
go.drugbank.com/drugs/DB01207ExperimentalRidogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction.
Categories: Heterocyclic Compounds, 1-Ring, Thromboxane-A Synthase, antagonists & inhibitorsDL-alpha tocopheryl acetate
go.drugbank.com/drugs/DB14477ApprovedMixtures: Prenate Max, Children's Chew Multi & Min TabCategories: Vitamin E