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Displaying results 2391 - 2400 of 10000 in total
  1. Target

    Potassium voltage-gated channel subfamily A member 10

    go.drugbank.com/bio_entities/BE0004720
    TargetHumans

    Voltage-gated potassium ion channel that mediates K(+) permeability of excitable membranes. When opened in response to the voltage difference across the membrane, KCNA10 channel selectively allows the flow of potassium ions across the me...

    Polypeptides: Potassium voltage-gated channel subfamily A member 10
  2. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

    go.drugbank.com/bio_entities/BE0000245
    TargetHumans

    Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of e...

    Polypeptides: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
  3. Target

    ATP-binding cassette sub-family C member 10

    go.drugbank.com/bio_entities/BE0003651
    TransporterHumans

    ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates s...

    Polypeptides: ATP-binding cassette sub-family C member 10
  4. Drug

    Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen

    go.drugbank.com/drugs/DB16714
    ApprovedInvestigational

    * serotype 10A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of *Corynebacterium diphtheriae* strain C7 (β197). … Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae

    Synonyms: Streptococcus pneumoniae type 10A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
  5. Drug

    Fluoroestradiol F-18

    go.drugbank.com/drugs/DB15690
    ApprovedInvestigational

    Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to v...

  6. Drug

    Me-4(18F)DG

    go.drugbank.com/drugs/DB19207
    Investigational

    Me-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).

  7. Pathway

    Acylcarnitine (10Z)-Pentadec-10-enoylcarnitine

    smpdb.ca/view/SMP0124228
    Metabolic

    (10Z)-Pentadec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z)-pentadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-pentadec-10-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  8. Pathway

    Acylcarnitine (10Z)-heptadec-10-enoylcarnitine

    smpdb.ca/view/SMP0124309
    Metabolic

    (10Z)-heptadec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z)-heptadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-heptadec-10-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  9. Pathway

    Acylcarnitine (10Z)-nonadec-10-enoylcarnitine

    smpdb.ca/view/SMP0124356
    Metabolic

    (10Z)-nonadec-10-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (10Z)-nonadec-10-enoyl-CoA reacts with L-carnitine to form (10Z)-nonadec-10-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Drug

    Amcipatricin

    go.drugbank.com/drugs/DB12333
    Investigational

    SPK-843 doses of higher than 1.0 mg/kg of body weight exhibit no renal toxicities and a tendency toward better survival prolongation than the estimated maximum tolerated doses of amphotericin B (Fungizone … Amcipatricin (as amcipatricin diascorbate; SPK-843) is a water-soluble partricin derivative patented by SPA Societa Prodotti Antibiotici S.p.A. and developed by Aparts and Kaken for the potential treatment