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Metastatic Colorectal Cancer (CRC)
go.drugbank.com/conditions/DBCOND0134580Synonyms: Metastasis to large intestine, Metastases to large intestineVorapaxar
go.drugbank.com/drugs/DB09030Approvedhimbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI … By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Synonyms: [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto[2,3-c]furan-6-yl]carbamate d'éthyle, Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl esterCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedSodium hydroxide is generally used as a solid or a diluted in a 50% solution. This chemical is used to manufacture soaps, rayon, paper, explosives, dyestuffs, and petroleum products [L1965]. … The use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay [A32334].
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% EMobocertinib
go.drugbank.com/drugs/DB16390ApprovedInvestigationalWithdrawn1.5- to 10-fold lower than those required to inhibit wild-type EGFR. … as compared to "classical" _EGFR_ mutants causing NSCLC) and are associated with resistance to standard targeted EGFR inhibitors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCancer Pain
go.drugbank.com/conditions/DBCOND0037097Synonyms: Pain Related to Cancer, Pain related to neoplasmInfluenza A virus A/Christchurch/16/2010 NIB-74 (H1N1) hemagglutinin antigen (propiolactone inactivated)
go.drugbank.com/drugs/DB14391ApprovedVaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen … that it was previously exposed to.
Synonyms: Influenza A virus A/Christchurch/16/2010 NIB-74 (H1N1) hemagglutinin antigen (propiolactone inactivated)Resolvin E1
go.drugbank.com/drugs/DB13105InvestigationalResolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
Synonyms: 5S,12R,18R-TRIHYDROXY-6Z,8E,10E,14Z,16E-EICOSAPENTAENOIC ACID, (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-TRIHYDROXY-6,8,10,14,16-EICOSAPENTAENOIC ACIDSalts: TP-317Elbasvir
go.drugbank.com/drugs/DB11574Approvedfor genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment. … [A19593] Substitutions at amino acid positions 28, 30, 31, or 93 are known to confer resistance to elbasvir.
Mixtures: ZEPATIER 50 MG/100 MG FİLM KAPLI TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsMethacholine
go.drugbank.com/drugs/DB06709Approved[A229598, A229603] Although the underlying pathology of AHR is complex, ASM contraction can be stimulated by cholinergic agonists that activate M<sub>3</sub> muscarinic receptors that stimulate ASM contraction … [L31763] In patients with AHR, a lower dose of methacholine is required to induce bronchoconstriction, which forms the basis for the methacholine challenge test to diagnose AHR.
Products: Sterile Provocholine Solution 16Aspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Mixtures: PEDASEL %10 AMİNO ASİT ÇÖZELTİSİ, 100 ML, PRIMENE %10 İNFÜZYONLUK PEDİYATRİK AMİNOASİT ÇÖZELTİSİ, 100 ML