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Cefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnAs part of its drug class, it shares structural properties to [cefalexin] as well as its activity spectrum. It was used in Italy but has since been withdrawn.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseTipiracil
go.drugbank.com/drugs/DB09343ApprovedInvestigationalIt is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. … [A31255] TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, or with an anti-VEGF
Alfuzosin
go.drugbank.com/drugs/DB00346ApprovedThe prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow.
Products: Alfuzosin PH&T 10mg prolonged-release tabletsFormestane
go.drugbank.com/drugs/DB08905ApprovedWithdrawnIt is listed as a prohibited substance by the World Anti-Doping Agency for use in athletes. … Currently, formestane (categorized as an anti-estrogenic agent) is prohibited from use in sports in accordance to the regulations of the World Anti-Doping Agency.
AstraZeneca COVID-19 Vaccine
go.drugbank.com/drugs/DB15656ApprovedInvestigationalThe AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2. … Despite these concerns, the EMA concluded its review by reiterating that the benefits of the vaccine in the prevention of COVID-19 - a condition which itself leads to blood clots - continue to outweigh
Categories: Experimental Unapproved Treatments for COVID-19Letterer-Siwe disease
go.drugbank.com/conditions/DBCOND0021755Drugs: VinblastineSynonyms: Langerhans cell histiocytosis, no International Classification of Diseases for Oncology subtypeLymphoma, Diffuse
go.drugbank.com/conditions/DBCOND0036855Synonyms: Non-Hodgkin lymphoma, no International Classification of Diseases for Oncology subtypeNon-Hodgkin's Lymphoma (NHL)
go.drugbank.com/conditions/DBCOND0030854Synonyms: Non-Hodgkin lymphoma, no International Classification of Diseases for Oncology subtypeAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational[A178090] Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum. … The non-stimulant norepinephrine/dopamine reuptake inhibitor [DB01156] (commonly used for the treatment of depression and for smoking cessation) has also been shown to be effective in the treatment of
Categories: Psychostimulants, Agents Used for ADHD and NootropicsTizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalTizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons
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