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Casein kinase I isoform alpha
go.drugbank.com/bio_entities/BE0009427TargetHumansCasein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (PubMed:11955436, PubMed:1409656, PubMed:18305108, PubMed:23902688). Phosphorylates a large number of proteins (P...
Polypeptides: Casein kinase I isoform alphaEukaryotic initiation factor 4A-I
go.drugbank.com/bio_entities/BE0008973TargetHumansATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome (PubMed:20156963). In the current model of translation initiation, eIF4A unwinds RNA secondary st...
Polypeptides: Eukaryotic initiation factor 4A-ISynonyms: eIF4A-I, eIF-4A-IKeratin, type I cytoskeletal 12
go.drugbank.com/bio_entities/BE0004660TargetHumansStructural component of intermediate filaments in the corneal epithelium. Forms heteropolymers with the type II keratin KRT3, assembling into keratin intermediate filament networks that provide mechanical strength and structural integrit...
Polypeptides: Keratin, type I cytoskeletal 12Herpes simplex type I reactivation
go.drugbank.com/conditions/DBCOND0025063Drugs: AcyclovirSynonyms: Herpes simplex type I reactivationLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer. … [A178123] Interestingly, levamisole has been found as an adulterant in cocaine and can lead to a variety of adverse effects in individuals using this drug.[A178120]
Categories: Heterocyclic Compounds, 1-RingProducts: OBAT CACING NO.17 KAM CEK SAN, PVP- LEVAMISOLE POUR-ON SOLUTION 20 %w/vBuprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approvedCombination with naloxone is intended to reduce the abuse potential of Suboxone, as naloxone is poorly absorbed by the oral route (and has no effect when taken orally), but would reverse the opioid agonist … [A186263,A186266,A186269] Buprenorphine acts as a partial mu-opioid receptor agonist with a high affinity for the receptor, but lower intrinsic activity compared to other full mu-opioid agonists such
Mixtures: SUBOXONE 8 MG/2 MG DILALTI TABLET, 7 ADET, Suboxone 8 mg/2 mg sublingual tabletsCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Drugs Used in Opioid DependencePentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigational[A226608] Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant Pharmaceuticals and APOTEX have been available since the late 1990s.[L30300]
Mixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesNo initial therapy
go.drugbank.com/conditions/DBCOND0106200Drugs: TelmisartanSynonyms: No initial therapyHydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigational[A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984.[L5795] … Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: 6-Deoxy-7,8-dihydro-6-oxomorphine, 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-onePotassium nitrate
go.drugbank.com/drugs/DB11090ApprovedInvestigationalIn addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. It is administered orally doses up to 30 g per animal per day [L1736]. … Potassium nitrate is an inorganic salt with a chemical formula of KNO3.
Mixtures: DOLNI - K GEL CON FLUOR, DOLNI-K GEL CON FLUORUROCategories: Compounds used in a research, industrial, or household setting