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Displaying results 251 - 260 of 1640 in total
  1. Drug

    Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

    go.drugbank.com/drugs/DB16709
    Approved

    The product does not remain permanently engrafted, instead being replaced by the patient's own cells over time, which can reduce or even eliminate the need for autografting.

  2. Drug

    Phenolphthalein

    go.drugbank.com/drugs/DB04824
    ApprovedWithdrawn

    Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.

  3. Drug

    Iluzanebart

    go.drugbank.com/drugs/DB18275
    Investigational

    Synonyms: Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain
  4. Drug

    Mepyramine

    go.drugbank.com/drugs/DB06691
    ApprovedVet approved

    It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. … Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.

    Mixtures: A-Tan 12X Suspension, Chlor-Tan A 12 Suspension
  5. Target

    Adenosine receptor A1

    go.drugbank.com/bio_entities/BE0000013
    TargetHumans

    Receptor for adenosine (PubMed:29925945). The activity of this receptor is mediated by G proteins such as GNAI2 which inhibit adenylyl cyclase

    Polypeptides: Adenosine receptor A1Function: G protein-coupled adenosine receptor activity
  6. Target

    Histamine H2 receptor

    go.drugbank.com/bio_entities/BE0000112
    TargetHumans

    G protein-coupled receptor for histamine, primarily mediating gastric acid secretion.

    Polypeptides: Histamine H2 receptorSynonyms: Gastric receptor I
  7. Target

    Histamine H4 receptor

    go.drugbank.com/bio_entities/BE0000146
    TargetHumans

    G protein-coupled receptor primarily expressed in immune cells such as mast cells, eosinophils, basophils, dendritic cells and neutrophils that plays a key role in immune and inflammatory responses (PubMed

    Polypeptides: Histamine H4 receptorSynonyms: G protein-coupled receptor 105
  8. Target

    Vasopressin V1a receptor

    go.drugbank.com/bio_entities/BE0000165
    TargetHumans

    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

    Polypeptides: Vasopressin V1a receptorSynonyms: Antidiuretic hormone receptor 1a, Vascular/hepatic-type arginine vasopressin receptor
  9. Target

    Prostaglandin D2 receptor

    go.drugbank.com/bio_entities/BE0000296
    TargetHumans

    Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.

    Polypeptides: Prostaglandin D2 receptorSynonyms: PGD receptor, PGD2 receptor
  10. Target

    Adenosine receptor A3

    go.drugbank.com/bio_entities/BE0000354
    TargetHumans

    In lung mast cells, receptor activation contributes to the type I allergic response by facilitating mast cell degranulation and histamine release (By similarity). … G protein-coupled receptor (GPCR) for adenosine that plays significant roles in various physiological processes including immune regulation, cardioprotection and neuroprotection (PubMed:38627384, PubMed

    Polypeptides: Adenosine receptor A3Function: G protein-coupled adenosine receptor activity