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Displaying results 2681 - 2690 of 10000 in total
  1. Target

    Deoxyuridine 5'-triphosphate nucleotidohydrolase

    go.drugbank.com/bio_entities/BE0003348
    TargetPlasmodium falciparum (isolate 3D7)

    Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

    Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolaseSynonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
  2. Target

    Pyridoxine 5'-phosphate phosphatase

    go.drugbank.com/bio_entities/BE0004713
    EnzymeEnsifer meliloti

    Polypeptides: Pyridoxine 5'-phosphate phosphatase
  3. Target

    Inosine-5'-monophosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0004941
    TargetHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays … Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase 1, Inosine-5'-monophosphate dehydrogenase 2Synonyms: Inosine-5'-monophosphate dehydrogenase type II
  4. Target

    Laminin subunit alpha-5

    go.drugbank.com/bio_entities/BE0002103
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a...

    Polypeptides: Laminin subunit alpha-5
  5. Target

    5-hydroxytryptamine receptor 3E

    go.drugbank.com/bio_entities/BE0009586
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3ESynonyms: 5-HT3E, 5-HT3-E
  6. Target

    5-hydroxytryptamine receptor 3B

    go.drugbank.com/bio_entities/BE0009583
    TargetHumans

    Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 3BSynonyms: 5-HT3B, 5-HT3-B
  7. Target

    Tryptophan 5-hydroxylase 1

    go.drugbank.com/bio_entities/BE0000121
    TargetEnzymeHumans

    Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis

    Polypeptides: Tryptophan 5-hydroxylase 1Synonyms: Tryptophan 5-monooxygenase 1
  8. Target

    Somatostatin receptor type 5

    go.drugbank.com/bio_entities/BE0002147
    TargetHumans

    Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization

    Polypeptides: Somatostatin receptor type 5Synonyms: SS-5-R
  9. Target

    Toll-like receptor 5

    go.drugbank.com/bio_entities/BE0011820
    TargetHumans

    Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response (PubMed:11323673, PubMed:18490781). Recognizes small molecular motifs named pathogen-associat...

    Polypeptides: Toll-like receptor 5
  10. Target

    Cytosolic purine 5'-nucleotidase

    go.drugbank.com/bio_entities/BE0000261
    TargetEnzymeHumans

    Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705).

    Polypeptides: Cytosolic purine 5'-nucleotidaseSynonyms: High Km 5'-nucleotidase, Cytosolic 5'-nucleotidase II