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Diclofenac Action Pathway
smpdb.ca/view/SMP0000093Drug actionDiclofenac (also named Voltaren) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to treat prostaglandin G/H synthase related fever, swelling, pain and inflammation. Diclofenac can block prostaglandin synthesis by the act...
Enzymes: Prostaglandin E synthaseKetorolac Action Pathway
smpdb.ca/view/SMP0000098Drug actionKetorolac (also named Toradol) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic), reduce fever (antipyretic) and swelling. Ketorolac can block prostaglandin synthesis by the action of inhibition...
Enzymes: Prostaglandin E synthaseSuprofen Action Pathway
smpdb.ca/view/SMP0000101Drug actionSuprofen (also named Profenal and Maldocil) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic) and reduce fever (antipyretic). Suprofen is also a type of ophthalmic anti-inflammatory medicines wh...
Enzymes: Prostaglandin E synthaseNabumetone Action Pathway
smpdb.ca/view/SMP0000114Drug actionNabumetone (also named Relafen and Relifex) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used to relieve pain (analgesic) and reduce fever (antipyretic). Nabumetone can block prostaglandin synthesis by the action of inhibi...
Enzymes: Prostaglandin E synthaseValdecoxib Action Pathway
smpdb.ca/view/SMP0000116Drug actionValdecoxib, a selective prostaglandin G/H synthase 2 (better known as cyclooxygenase-2 or COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Valdecoxib was used for its anti-inflammatory, analgesic, and ant...
Enzymes: Prostaglandin E synthaseLeukotriene C4 Synthesis Deficiency
smpdb.ca/view/SMP0000353DiseaseLeukotriene C4 synthetase deficiency is caused by a defect in the enzyme leukotriene C4 synthetase (LTC4S). This enzyme catalyzes the synthesis of leukotriene C4 (LTC4) through conjugation of LTA4 with reduced glutathione (GSH), which is...
Enzymes: Prostaglandin E synthaseAntipyrine Action Pathway
smpdb.ca/view/SMP0000692Drug actionAntipyrine (also named Fenazone or Phenazone) is often used for testing the effect of other drugs on drug-metabolizing enzymes in the liver. Antipyrine can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H sy...
Enzymes: Prostaglandin E synthaseAntrafenine Action Pathway
smpdb.ca/view/SMP0000693Drug actionAntrafenine (also named Stakane) acts as an anti-inflammatory and analgesic drug. It is not widely used as it has largely been replaced by newer drugs. Antrafenine can block prostaglandin synthesis by the action of inhibition of prostagl...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Antrafenine +5 moreEnzymes: Prostaglandin E synthaseCarprofen Action Pathway
smpdb.ca/view/SMP0000694Drug actionCarprofen (also named Rimadyl or Imadyl) is a nonsteroidal anti-inflammatory drug that can treat various joint pain or post-operative pain. Carprofen can block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synt...
Enzymes: Prostaglandin E synthaseLumiracoxib Action Pathway
smpdb.ca/view/SMP0000699Drug actionLumiracoxib (also named Prexige) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used as the mediators of certain kinds of intraocular inflammation. Lumiracoxib can block prostaglandin synthesis by the action of inhibition of...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Lumiracoxib · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthase