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Uroporphyrinogen decarboxylase
go.drugbank.com/bio_entities/BE0001629TargetHumansCatalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:11069625, PubMed:11719352, PubMed:1463398...
Synonyms: UPDVomit
go.drugbank.com/conditions/DBCOND0052584Synonyms: Throwing up, (Vomiting) or (bilious attack) or (throwing up)Chlorphentermine
go.drugbank.com/drugs/DB01556ApprovedIllicitWithdrawnA sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension.
Flibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalin the brain as well as an effect on increasing norepinephrine and dopamine neurotransmitters. … It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder drug by Sprout Pharmaceuticals
Categories: Serotonin Receptor Agonists, Serotonin Receptor AntagonistsSusoctocog alfa
go.drugbank.com/drugs/DB11606ApprovedInvestigationalIn a global, prospective, controlled, multi-center Phase 2/3 open-label clinical trial, all patients responded to susoctocog alfa treatment within 24 hours [L1129]. … AHA is a rare bleeding disorder that results in a prolonged clotting time as measured by the activated partial thromboplastin time (aPTT) assay, a conventional in vitro test for biological activity of
Synonyms: RECOMBINANT DNA DERIVED B-DOMAIN DELETED PORCINE BLOODCOAGULATION FACTOR VIII ANALOGUE, PRODUCED IN BHK21 CELLS: DES-(753-1418)-BLOOD-COAGULATION FACTOR VIII (PROCOAGULANT COMPONENT) SUS SCROFA, GLYCOSYLATEDDeucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigational[L43150] It was later approved by Health Canada in November 2022 [L44216] and by the European Medicines Agency in March 2023.[L45788] … Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor.
Warfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalWarfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. … Warfarin has several properties that should be noted when used medicinally, including its ability to cross the placental barrier during pregnancy which can result in fetal bleeding, spontaneous abortion
Categories: Compounds used in a research, industrial, or household setting, Vitamin K InhibitorsMethyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigational[A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent.
Categories: Adrenergic alpha-2 Receptor AgonistsProducts: METILDOPA MK 250 MG TABLETASCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigational[A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in the colon. … [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998.
Gadoteridol
go.drugbank.com/drugs/DB00597ApprovedInvestigationalgadolinium in the brain. … [A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876]
Categories: Compounds used in a research, industrial, or household setting