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Acute Myocardial Infarction (AMI)
go.drugbank.com/conditions/DBCOND0032772Synonyms: Acute myocardial infarction, unspecified site, Acute myocardial infarction, unspecified site, episode of care unspecifiedLovastatin Action Pathway (New)
smpdb.ca/view/SMP0124570Drug actionStatins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it.
Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 proteaseRosuvastatin
smpdb.ca/view/SMP0124577Drug actionStatins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it.
Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 proteaseSimvastatin Action Pathway (New)
smpdb.ca/view/SMP0124578Drug actionStatins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it.
Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 proteaseOmega-3-carboxylic acids
go.drugbank.com/drugs/DB09568ApprovedWithdrawnThe omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of p...
Hexafluronium
go.drugbank.com/drugs/DB00941ApprovedHexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. It is known to bind and block the activity of plasma cholineste...
Atorvastatin Action Pathway (New)
smpdb.ca/view/SMP0124555Drug actionStatins bind reversibly to the active site of HMG-CoA reductase and the subsequent structural change in the enzyme effectively disables it.
Enzymes: Membrane-bound transcription factor site-2 protease, Membrane-bound transcription factor site-1 proteaseBacillus calmette-guerin substrain connaught live antigen
go.drugbank.com/drugs/DB10804ApprovedInvestigationalWithdrawnBacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary
Troleandomycin
go.drugbank.com/drugs/DB13179ApprovedA macrolide antibiotic that is similar to erythromycin.
Teicoplanin
go.drugbank.com/drugs/DB06149ApprovedInvestigationalWithdrawnAll teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety. … Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4).