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Displaying results 2801 - 2810 of 10000 in total
  1. Drug

    Chymopapain

    go.drugbank.com/drugs/DB06752
    ApprovedWithdrawn

    [L2482]It is an extracellular plant cysteine proteinase similar to papain in specificity.[A32688] Chymopapain was developed by Chart Medcl and FDA approved on November 10, 1982. … Chymopapain was first isolated in 1941 from the crude latex derived from the fruit of Carica papaya by squeezing the green papaya while on the plant prior to harvest.

  2. Target

    Ubiquitin-conjugating enzyme E2 T

    go.drugbank.com/bio_entities/BE0019778
    TargetHumans

    In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:20061386) … May contribute to ubiquitination and degradation of BRCA1 (PubMed:19887602).

    Synonyms: Cell proliferation-inducing gene 50 protein
  3. Drug

    Lactobacillus plantarum

    go.drugbank.com/drugs/DB11360
    Investigational

    It is considered to be one of versatile species that carry out fermentative and metabolic processes, while exhibiting an antagonistic activity against pathogenic and spoilage microorganisms.

    Mixtures: BİOBER-ZN ORAL SÜSPANSİYON İÇEREN FLAKON, 5 ADETProducts: Kimchi Lactic Acid 1000, Kimchi Lactobacillus 1000
  4. Drug

    Solenopsis richteri

    go.drugbank.com/drugs/DB11026
    Approved

    It is extracted from the black imported fire ant which is native to South Amercia. The species has also been introduced in North Amercia. … When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with redness extending beyond.

    Synonyms: black imported fire ant allergenic extractMixtures: Insects whole body, Fire Ant Mix, Insects whole body, Fire Ant Mix
  5. Drug

    Viltolarsen

    go.drugbank.com/drugs/DB15005
    ApprovedInvestigational

    Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function … for exon 53 skipping.

    Synonyms: Exon 53 specific antisense morpholino oligonucleotide
  6. Indication

    Lactose Malabsorption

    go.drugbank.com/conditions/DBCOND0056783
    Drugs: Tilactase
    Synonyms: Intolerance to lactose (finding)
  7. Indication

    Trichomonas Vaginalis Infection

    go.drugbank.com/conditions/DBCOND0044722
    Drugs: Diiodohydroxyquinoline · Policresulen · Tinidazole
    Synonyms: Disease due to Trichomonadidae (disorder)
  8. Indication

    Acquired Coagulation Factor Deficiency

    go.drugbank.com/conditions/DBCOND0032166
    Drugs: Coagulation factor X human · Plasma protein fraction (human)
    Synonyms: Deficiency of coagulation factor due to liver disease (disorder), Deficiency of coagulation factor due to vitamin K deficiency (disorder)
  9. Target

    Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

    go.drugbank.com/bio_entities/BE0004448
    TargetHumans

    GSPT1/ERF3A mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site (PubMed:27863242). … GTP hydrolysis by GSPT1/ERF3A induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site (PubMed:16777602, PubMed:27863242).

    Synonyms: G1 to S phase transition protein 1 homolog
  10. Indication

    Alcohol Problem Drinking

    go.drugbank.com/conditions/DBCOND0132393
    Drugs: Disulfiram
    Synonyms: [X]Mental and behavioral disorders due to use of alcohol: dependence syndrome, [X]Mental and behavioural disorders due to use of alcohol: dependence syndrome