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Displaying results 2811 - 2820 of 10000 in total
  1. Target

    Protein-glutamine gamma-glutamyltransferase 5

    go.drugbank.com/bio_entities/BE0002236
    EnzymeHumans

    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes

    Polypeptides: Protein-glutamine gamma-glutamyltransferase 5Synonyms: TGase-5, Transglutaminase-5
  2. Target

    Excitatory amino acid transporter 5

    go.drugbank.com/bio_entities/BE0002267
    TargetHumans

    Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions a...

    Polypeptides: Excitatory amino acid transporter 5
  3. Target

    Serine/threonine-protein phosphatase 5

    go.drugbank.com/bio_entities/BE0003160
    TargetHumans

    Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD p...

    Polypeptides: Serine/threonine-protein phosphatase 5
  4. Target

    Interleukin-5 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0003471
    TargetHumans

    Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1495999, PubMed:22528658).

    Polypeptides: Interleukin-5 receptor subunit alphaSynonyms: IL-5 receptor subunit alpha
  5. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0003891
    TargetVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

    Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase
  6. Target

    Proteasome subunit alpha type-5

    go.drugbank.com/bio_entities/BE0003914
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...

    Polypeptides: Proteasome subunit alpha type-5Synonyms: alpha-5, Proteasome subunit alpha-5
  7. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0004031
    TargetEscherichia coli O157:H7

    Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. … Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase
  8. Target

    Keratin-associated protein 5-2

    go.drugbank.com/bio_entities/BE0004492
    TargetHumans

    In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through ...

    Polypeptides: Keratin-associated protein 5-2Synonyms: Keratin-associated protein 5-8
  9. Target

    5'(3')-deoxyribonucleotidase, cytosolic type

    go.drugbank.com/bio_entities/BE0004774
    EnzymeHumans

    Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP (Ref.12).

    Polypeptides: 5'(3')-deoxyribonucleotidase, cytosolic typeSynonyms: Deoxy-5'-nucleotidase 1, Cytosolic 5',3'-pyrimidine nucleotidase
  10. Target

    5'-AMP-activated protein kinase

    go.drugbank.com/bio_entities/BE0004907
    TargetTransporterHumans

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:17307971, PubMed:17712357, PubMed:24563466, PubMed:31492851, PubMed:37821951...

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit beta-2