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Displaying results 2821 - 2830 of 10000 in total
  1. Pathway

    Phosphatidylethanolamine Biosynthesis PE(18:3(9Z,12Z,15Z)/15:0)

    smpdb.ca/view/SMP0015347
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more
  2. Pathway

    Acylcarnitine (5Z,8Z,11Z,13E,15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoylcarnitine

    smpdb.ca/view/SMP0123544
    Metabolic

    (5Z,8Z,11Z,13E,15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (5Z,8Z,11Z,13E,15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoyl-CoA reacts with L-carnitine to form (5Z,8Z,11Z,13E,15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoylcarnitine

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Drug

    Rhubarb

    go.drugbank.com/drugs/DB10651
    Approved

    Rhubarb allergenic extract is used in allergenic testing.

    Mixtures: ORALDIN ÇÖZELTI ,10 ML-1 ŞIŞE, PIRALDYNE ORAL SOLUSYON 10 ML
  4. Drug

    Prasterone

    go.drugbank.com/drugs/DB01708
    ApprovedInvestigationalNutraceutical

    In November 2016, DHEA was approved (as Intrarosa) to treat women experiencing moderate to severe pain during sexual intercourse (dyspareunia), a symptom of vulvar and vaginal atrophy (VVA), due to menopause … In Canada, a prescription is required to buy DHEA.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsInternational brands: OVIGYN-D
  5. Pathway

    Phosphatidylcholine Biosynthesis PC(18:3(9Z,12Z,15Z)/15:0)

    smpdb.ca/view/SMP0014507
    Metabolic

    Phosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. They are the most abundant phospholipid in eukaryotic cell membranes and has both structural and signallin...

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  6. Drug

    Amoxapine

    go.drugbank.com/drugs/DB00543
    Approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … See toxicity section below for a complete listing of side effects.

    Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Dopamine D2 Receptor Antagonists
  7. Drug

    Vernakalant

    go.drugbank.com/drugs/DB06217
    ApprovedInvestigational

    Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. … It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  8. Drug

    Hydrocortisone cypionate

    go.drugbank.com/drugs/DB14541
    ApprovedVet approvedWithdrawn

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers
  9. Drug

    Leronlimab

    go.drugbank.com/drugs/DB05941
    Investigational

    Leronlimab, or PRO-140, is a human monoclonal antibody developed by CytoDyn.[L12684] It was first described in the literature in 2001.

  10. Drug

    BGB-DXP593

    go.drugbank.com/drugs/DB16357
    Investigational

    BGB-DXP593 is a SARS-CoV-2 neutralizing antibody. … [L27401] It is currently being investigated against COVID-19 in the clinical trial NCT04551898 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants