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Daprodustat
go.drugbank.com/drugs/DB11682ApprovedInvestigationalanemia of CKD but not for non-dialysis patients with anemia of CKD. … [L43857] On February 1, 2023, daprodustat was fully approved by the FDA as the first oral treatment for anemia caused by chronic kidney disease in patients on dialysis.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsSynonyms: Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)-Pepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnPepsin is approved by the FDA and is used in food at levels not to exceed current good manufacturing practice [L2363]. … Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products [L2358].
Mixtures: Betaine HCl and Pepsin, Pancreatin and Enzyme Formula - TabletCategories: Enzymes and Coenzymes, Alimentary Tract and MetabolismAcetyl sulfisoxazole
go.drugbank.com/drugs/DB14033ApprovedVet approvedThis process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, resulting in cell growth arrest and cell death [L2788]. … Sulfisoxazole acetyl is an ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity.
Mixtures: Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl, Erythromycin Ethylsuccinate and Sulfisoxazole AcetylCategories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and AntisepticsMagnesium silicate
go.drugbank.com/drugs/DB13249ApprovedWithdrawnThe molecular formula can be expressed more clearly as MgSiO3.xH2O.[T186] It is known as talc and it presents many uses in the cosmetic industry, food industry and pharmaceutical industry. … Magnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water.
Categories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsBack pain
go.drugbank.com/conditions/DBCOND0115953Drugs: Acetaminophen · Borneol · Camphor · Capsaicin · Choline salicylate · Chondroitin sulfate +11 moreSynonyms: Pain in backAcipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalAcipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL. … Adverse effects include flushing (associated with Prostaglandin D2), palpitations, and GI disturbances. Flushing can be reduced by taking aspirin 20-30 min before taking Acipimox.
Categories: Nicotinic Acid and DerivativesGalactose
go.drugbank.com/drugs/DB11735ApprovedInvestigationalWithdrawnRegardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products … Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer, Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others.
Mixtures: Levovist - Pws IV (4g Granules /vial)Pidolic acid
go.drugbank.com/drugs/DB03088ApprovedInvestigationalPidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form, like skin [L2729].
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and Proteinsgamma-Hydroxybutyric acid
go.drugbank.com/drugs/DB01440ApprovedIllicitInvestigationalIt is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). … It is used illegally under the street names Juice, Liquid Ecstasy or simply G, either as an intoxicant, or as a date rape drug.
Synonyms: oxy-n-butyric acidEflapegrastim
go.drugbank.com/drugs/DB15001ApprovedInvestigational[L43135] In September 2022, eflapegrastim was approved by the US FDA as a prophylactic against infection, as manifested by febrile neutropenia, in patients receiving certain myelosuppressive anti-cancer … in which the patient develops an infection during a period of significant neutropenia.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents