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Ansuvimab
go.drugbank.com/drugs/DB16385ApprovedInfection with pathogenic filoviruses, such as _Zaire ebolavirus_ (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as … [A207646] Ansuvimab received FDA approval on December 21, 2020, and is currently marketed as Ebanga by Ridgeback Biotherapeutics, LP. Ansuvimab is just the second FDA-approved treatment for EVD.
Categories: Amino Acids, Peptides, and Proteins, Immune Sera and ImmunoglobulinsFerric pyrophosphate
go.drugbank.com/drugs/DB09147ApprovedInvestigationalThe ferric ion is strongly complexed by pyrophosphate.[A31979] It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability. … Free iron presents several side effects as it can catalyze free radical formation and lipid peroxidation as well as the presence of interactions of iron in plasma.
Inosine
go.drugbank.com/drugs/DB04335ApprovedIt is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. … A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose.
Categories: Genito Urinary System and Sex Hormones, Gynecological Antiinfectives and AntisepticsSynonyms: INOFredrickson Type III lipidemia
go.drugbank.com/conditions/DBCOND0106234Drugs: AtorvastatinSynonyms: Familial hyperbetalipoproteinemia and hyperprebetalipoproteinemia, Familial hyperbetalipoproteinaemia and hyperprebetalipoproteinaemiaLower Respiratory Tract Infections
go.drugbank.com/conditions/DBCOND0052142Synonyms: Lower Respiratory Tract and Lung Infections, Lower respiratory tract and lung infectionRespiratory Tract Diseases
go.drugbank.com/conditions/DBCOND0029282Synonyms: Respiratory, thoracic, and mediastinal disorders, Respiratory, thoracic and mediastinal disordersWP-1122
go.drugbank.com/drugs/DB17192InvestigationalWP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361]
Synonyms: an acetic acid diester of 2-deoxy-D-glucoseRiltozinameran
go.drugbank.com/drugs/DB17095ApprovedInvestigational[L43922] It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). … [L43917] Riltozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineage BA.1.
AstraZeneca COVID-19 Vaccine
go.drugbank.com/drugs/DB15656ApprovedInvestigational[L12669] The trial is taking place in the UK, where the vaccine will be administered intramuscularly to healthy adult volunteers between the ages of 18 and 55.[L12669] … across the globe, including Canada, Mexico, the UK, the EU, and Australia, amongst others.
Synonyms: AZD-1222Mirvetuximab soravtansine
go.drugbank.com/drugs/DB12489ApprovedInvestigationalMirvetuximab soravtansine-gynx (IMGN853) is an antibody-drug conjugate (ADC) formed by a monoclonal antibody (M9346A) that targets folate receptor alpha (FRα), covalently joined by a cleavable disulfide … [A254382] After an ADC/receptor complex is formed, mirvetuximab soravtansine-gynx is internalized, and DM4 is released inside the cell.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents