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Sertaconazole
go.drugbank.com/drugs/DB01153ApprovedSertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.
Categories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex HormonesAducanumab
go.drugbank.com/drugs/DB12274ApprovedInvestigational[L34420] Biogen enrolled patients in phase 3 clinical trials in 2015 but increased the size of the trials from 1350 patients to 1650 patients to maintain statistical power in the face of a high standard … [A235668,A235730] Aducanumab is a recombinant antibody derived from patients with slow or absent cognitive decline, and phase 1b clinical trial data have shown patients treated with aducanumab show a reduction
Categories: Amino Acids, Peptides, and ProteinsGlatiramer
go.drugbank.com/drugs/DB05259ApprovedInvestigational[A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. … Glatiramer acetate exhibits several immunomodulatory effects and reduces the relapse rate of relapsing-remitting multiple sclerosis (RRMS) by 30%.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawn[A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity. … [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects.
Categories: Bile Acids and Salts, Bile and Liver TherapyDienestrol
go.drugbank.com/drugs/DB00890ApprovedWithdrawnIt is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. … Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of the vulva.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemPruritus Ani
go.drugbank.com/conditions/DBCOND0005710Drugs: Aloe vera leaf · Aluminum subacetate · Benzalkonium · Bismuth subgallate · Bufexamac · Carvasept +8 moreSynonyms: Pruritus Ani, Pruritus ani (finding)Marstacimab
go.drugbank.com/drugs/DB17725ApprovedInvestigational[A264608] Marstacimab is used to prevent bleeding episodes in patients with hemophilia,[L51803] which is an X‐linked bleeding disorder characterized by coagulation clotting factor deficiency. … [L51803] It is a tissue factor pathway inhibitor (TFPI) antagonist, which is an endogenous anticoagulant.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsPolythiazide
go.drugbank.com/drugs/DB01324ApprovedA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Categories: polythiazide and potassium, Genito Urinary System and Sex HormonesAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalThe Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G). … [L43397] Alemtuzumab was approved by the FDA in 2001.[L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic lymphocytic leukemia (B-CLL).
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsDiffuse Large B-Cell Lymphoma (DLBCL)
go.drugbank.com/conditions/DBCOND0028221Synonyms: Malignant lymphoma, large cell, cleaved and noncleaved, Malignant lymphoma - large cell cleaved and non-cleaved