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Displaying results 3121 - 3130 of 10000 in total
  1. Drug

    Elexacaftor

    go.drugbank.com/drugs/DB15444
    ApprovedInvestigational

    produces proteins unresponsive to ivacaftor or tezacaftor. … [A187361] The triple combination product Trikafta<sup>TM</sup>, manufactured by Vertex Pharmaceuticals, is the first product approved for the treatment of CF in individuals who are either homo- _or_ heterozygous

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Substrates
  2. Drug

    Ethinamate

    go.drugbank.com/drugs/DB01031
    ApprovedIllicitWithdrawn

    Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. … Structurally, it does not resemble the barbituates, but it shares many effects with this class of drugs; the depressant effects of ethinamate are, however, generally milder than those of most barbiturates

  3. Drug

    Rutin

    go.drugbank.com/drugs/DB01698
    ApprovedInvestigational

    It has been used therapeutically to decrease capillary fragility.

    Synonyms: 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-oneMixtures: Nutriforte Non-Acidic Vitamin C 1000 mg with Bioflavonoids, NAT-C 1000
  4. Drug

    IR208

    go.drugbank.com/drugs/DB05106
    Investigational

    It contains three peptides (BV5S2, BV6S5 and BV13S1) expressed by T-Cells in over 90% of MS patients. IR208 is currently undergoing Phase II studies in a 200-patient trial. … IR208 is a synthetic T-Cell receptor peptide vaccine developed by Immune Response Corporation.

  5. Drug

    Umbralisib

    go.drugbank.com/drugs/DB14989
    ApprovedInvestigationalWithdrawn

    It was marketed as Ukoniq by TG Therapeutics and has been approved for the treatment of relapsing and refractory marginal cell lymphoma and follicular lymphoma in adults. … [A229668] On February 5, 2021, the Food and Drug Administration granted accelerated approval to umbralisib, a kinase inhibitor for PI3K-delta and casein kinase CK1-epsilon, based on promising results

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  6. Indication

    Second Degree Burns

    go.drugbank.com/conditions/DBCOND0057796
    Drugs: Centella asiatica · Nepidermin · Zinc oxide
    Synonyms: Blisters with epidermal loss due to burn (second degree), unspecified site
  7. Indication

    Hypoactive Sexual Desire Disorder (HSDD)

    go.drugbank.com/conditions/DBCOND0035717
    Drugs: Bremelanotide · Flibanserin
    Synonyms: Inability to enjoy sexual relations
  8. Indication

    Pediculosis Capitis

    go.drugbank.com/conditions/DBCOND0043220
    Drugs: Lindane
    Synonyms: Pediculosis due to Pediculus humanus capitis
  9. Indication

    Stomach ache

    go.drugbank.com/conditions/DBCOND0094525
    Drugs: Simethicone
    Synonyms: Pain localized to upper abdomen
  10. Indication

    Functional disorders of the biliary tract

    go.drugbank.com/conditions/DBCOND0023568
    Drugs: Phloroglucinol · Pinaverium
    Synonyms: Disease of biliary tract -RETIRED- Refer to D5-85001