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Spectinomycin
go.drugbank.com/drugs/DB00919ApprovedVet approvedWithdrawnIt is active against gram-negative bacteria and used for the treatment of gonorrhea.
Products: TROBICIN FOR INJECTION 2 g/vialMexiletine
go.drugbank.com/drugs/DB00379ApprovedInvestigationalAntiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Metaraminol
go.drugbank.com/drugs/DB00610ApprovedIt has been used primarily as a vasoconstrictor in the treatment of hypotension. … An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine.
Ceftobiprole medocaril
go.drugbank.com/drugs/DB14733ApprovedThe EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European … Ceftobiprole medocaril is a prodrug of [ceftobiprole], a fifth-generation semisynthetic cephalosporin antibacterial.
Products: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungKetazolam
go.drugbank.com/drugs/DB01587ApprovedWithdrawnKetazolam is not approved in Canada or America.
Trioxsalen
go.drugbank.com/drugs/DB04571ApprovedWithdrawnIt is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. … Like other psoralens it causes photosensitization of the skin.
mRNA-1345
go.drugbank.com/drugs/DB18739ApprovedInvestigational[L53393] It is the primary ingredient of the RSV vaccine mRESVIA. mRESVIA was first approved in the EU and US in 2024 for use in patients 60 years of age and older. … [L53403,L52380] In June 2025, its US indication was expanded to include patients 18-59 years old at increased risk of disease.
Interferon gamma-1b
go.drugbank.com/drugs/DB00033ApprovedInvestigationalProduction of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. … Purification of the product is achieved by conventional column chromatography.
Moxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalBayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Products: TABLET 400 MG, Ag-moxifloxacinEthotoin
go.drugbank.com/drugs/DB00754ApprovedThe mechanism of action is probably very similar to that of phenytoin. … The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges.