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Elvitegravir
go.drugbank.com/drugs/DB09101ApprovedInvestigationalElvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. It was FDA approved on August 27, 2012.
Doxapram
go.drugbank.com/drugs/DB00561ApprovedInvestigationalVet approvedA central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Pentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedThe first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Tramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalTramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the
Limaprost
go.drugbank.com/drugs/DB09211InvestigationalProstaglandins have a wide variety of actions, including, but not limited to muscular constriction and mediation of inflammation. … The drug has been sold under the trade name of Opalmon® Tablets by Ono and Prorenal® Tablets by DSP.
Edetate calcium disodium anhydrous
go.drugbank.com/drugs/DB14598ApprovedInvestigationalEdetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted F...
Sodium ferric gluconate complex
go.drugbank.com/drugs/DB09517ApprovedSodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons...
Rivoglitazone
go.drugbank.com/drugs/DB09200InvestigationalIt is being developed by Daiichi Sankyo Co.
Fosinoprilat
go.drugbank.com/drugs/DB14207ExperimentalFosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
VAD-044
go.drugbank.com/drugs/DB17697InvestigationalVAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098]