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Group 10 secretory phospholipase A2
go.drugbank.com/bio_entities/BE0000070TargetEnzymeHumansSecretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:12021277, PubMed:9188469). Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preferen...
Polypeptides: Group 10 secretory phospholipase A2Synonyms: Phosphatidylcholine 2-acylhydrolase 10Interleukin-10 receptor subunit alpha
go.drugbank.com/bio_entities/BE0014391TargetHumansCell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, all...
Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1Bcl-2-like protein 10
go.drugbank.com/bio_entities/BE0019838TargetHumansPromotes cell survival by suppressing apoptosis induced by BAX but not BAK (PubMed:11278245, PubMed:11689480). Increases binding of AHCYL1/IRBIT to ITPR1 (PubMed:27995898). Reduces ITPR1-mediated calcium release from the endoplasmic reti...
Polypeptides: Bcl-2-like protein 10Synonyms: Bcl2-L-10START domain-containing protein 10
go.drugbank.com/bio_entities/BE0021582TransporterHumansMay play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl cha...
Polypeptides: START domain-containing protein 10Synonyms: StAR-related lipid transfer protein 10Aldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalGenetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. … Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene.
Synonyms: ILT-101, 125-L-Serine-2-133-interleukin 2Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents5'-nucleotidase
go.drugbank.com/bio_entities/BE0001096TargetEnzymeHumansCatalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:22997138, PubMed:23142347, PubMed:24887587, PubMed:344...
Polypeptides: 5'-nucleotidaseSynonyms: 5'-NT, 5'-deoxynucleotidaseInterleukin-5
go.drugbank.com/bio_entities/BE0001208TargetHumansHomodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276). Also acts on activated and resting ...
Polypeptides: Interleukin-5Synonyms: IL-5Kallikrein-5
go.drugbank.com/bio_entities/BE0010708TargetHumansMay be involved in desquamation
Polypeptides: Kallikrein-5Micafungin
go.drugbank.com/drugs/DB01141ApprovedInvestigationalIt belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Categories: Amino Acids, Peptides, and ProteinsProducts: MYCAMINE FOR INJECTION 50 MG/VIAL, MSFUNGİN 50 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADETMaprotiline
go.drugbank.com/drugs/DB00934ApprovedMaprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). … Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.
Categories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Cytochrome P-450 SubstratesProducts: MAPROTILIN-NEURAX 50 MG, Ludiomil 50 mg - Filmtabletten