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Omega-3 fatty acids
go.drugbank.com/drugs/DB11133ApprovedInvestigationalNutraceuticalOmega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S. … Food and Drug Administration gave "qualified health claim" status to EPA and DHA omega-3 fatty acids.
Synonyms: n-3 PUFAs, n-3 fatty acidsMixtures: LIPOMEGA® 10, Lipidem 200mg/ml Emulsion for InfusionPitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.
Categories: pitavastatin and ezetimibe, Cytochrome P-450 SubstratesProducts: Trolise 1 mg Filmtabletten, PITAMIN 1 MG EFERVESAN TABLET, 30 ADETDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnA synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. … (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942]
Categories: Hormones and Related Agents, Antineoplastic and Immunomodulating AgentsSynonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexene, α,α'-diethyl-(E)-4,4'-stilbenediolEnoxacin
go.drugbank.com/drugs/DB00467ApprovedA broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Categories: Metabolic Side Effects of Drugs and Substances, 4-QuinolonesSynonyms: 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid, 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acidLomustine
go.drugbank.com/drugs/DB01206ApprovedInvestigationalAn alkylating agent of value against both hematologic malignancies and solid tumors.
Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexylnitrosoureaNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approvedNystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species. … [A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate
Mixtures: NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 12 ADET, NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 6 ADETCategories: Compounds used in a research, industrial, or household setting, Alimentary Tract and MetabolismPotassium channel subfamily K member 10
go.drugbank.com/bio_entities/BE0013513TargetHumansK(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens t...
Polypeptides: Potassium channel subfamily K member 10Acalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalAt this time, more than 35 clinical trials across 40 countries with more than 2500 patients are underway or have been completed with regards to further research into better understanding and expanding … or/and that fill an unmet medical need based on a surrogate endpoint.
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: CALQUENCE 100 MG SERT KAPSÜL, 56 ADET, CALQUENCE 100 MG SERT KAPSÜL, 60 ADETNeuronal acetylcholine receptor subunit alpha-10
go.drugbank.com/bio_entities/BE0000411TargetHumansComponent of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits. E...
Polypeptides: Neuronal acetylcholine receptor subunit alpha-10Synonyms: NACHR alpha-10, Nicotinic acetylcholine receptor subunit alpha-10C-X-C motif chemokine 10
go.drugbank.com/bio_entities/BE0000934TargetHumansPro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (PubMed:...
Polypeptides: C-X-C motif chemokine 10Synonyms: IP-10, 10 kDa interferon gamma-induced protein