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Displaying results 3341 - 3350 of 10000 in total
  1. Target

    Pseudouridine-5'-phosphatase

    go.drugbank.com/bio_entities/BE0014361
    EnzymeHumans

    Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine

    Polypeptides: Pseudouridine-5'-phosphataseSynonyms: 5'-PsiMPase, Pseudouridine-5'-monophosphatase
  2. Target

    NADPH oxidase 5

    go.drugbank.com/bio_entities/BE0018640
    TargetHumans

    Calcium-dependent NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor (PubMed:12686516). Also synthesizes NAADP from its reduced NAADPH form which promotes Ca(2+) signaling...

    Polypeptides: NADPH oxidase 5
  3. Target

    Camphor 5-monooxygenase

    go.drugbank.com/bio_entities/BE0001246
    TargetPseudomonas putida

    Involved in a camphor oxidation system.

    Polypeptides: Camphor 5-monooxygenaseFunction: camphor 5-monooxygenase activity
  4. Drug

    Daclatasvir

    go.drugbank.com/drugs/DB09102
    ApprovedInvestigationalWithdrawn

    Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. … Daclatasvir was FDA-approved in July 2015 for use with [DB08934] (Sovaldi) with or without [DB00811] to treat HCV genotype 1 and 3 infections.

    Categories: Heterocyclic Compounds, 1-Ring, Amino Acids, Peptides, and ProteinsProducts: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)
  5. Drug

    Potassium acetate

    go.drugbank.com/drugs/DB14498
    Approved

    Mixtures: Normosol-M and Dextrose, Normosol-M and DextroseCategories: Blood and Blood Forming Organs, Blood Substitutes and Perfusion Solutions
  6. Drug

    Lomustine

    go.drugbank.com/drugs/DB01206
    ApprovedInvestigational

    An alkylating agent of value against both hematologic malignancies and solid tumors.

    Synonyms: 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexylnitrosoureaCategories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2D6 Inhibitors
  7. Drug

    Acalabrutinib

    go.drugbank.com/drugs/DB11703
    ApprovedInvestigational

    At this time, more than 35 clinical trials across 40 countries with more than 2500 patients are underway or have been completed with regards to further research into better understanding and expanding … or/and that fill an unmet medical need based on a surrogate endpoint.

    Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: CALQUENCE 100 MG SERT KAPSÜL, 56 ADET, CALQUENCE 100 MG SERT KAPSÜL, 60 ADET
  8. Drug

    Hydrocortisone phosphate

    go.drugbank.com/drugs/DB14542
    ApprovedInvestigationalVet approved

    Categories: 11-Hydroxycorticosteroids, 17-HydroxycorticosteroidsProducts: Softacort 3,35 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis
  9. Pathway

    Acylcarnitine 10-Hydroxydodec-5-enedioylcarnitine

    smpdb.ca/view/SMP0124031
    Metabolic

    10-Hydroxydodec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-hydroxydodec-5-enedioyl-CoA reacts with L-carnitine to form 10-hydroxydodec-5-enedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  10. Drug

    Pirenoxine

    go.drugbank.com/drugs/DB15945
    Investigational

    Categories: Heterocyclic Compounds, 1-RingProducts: KARY UNI OPHTHALMIC SUSPENSION 0.05 mg/ml, KARY UNI