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Degarelix
go.drugbank.com/drugs/DB06699ApprovedInvestigationalDegarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. … Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which are D-amino acids. FDA approved on December 24, 2008.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: FIRMAGON Powder and Solvent for Solution for Injection 120 mg, FIRMAGON Powder and Solvent for Solution for Injection 80 mgOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigationalOzanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. … [A189336] In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard
Mixtures: ZEPOSIA 7-Day Starter Pack, ZEPOSIA 7-Day Starter PackCategories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsSodium channel protein type 10 subunit alpha
go.drugbank.com/bio_entities/BE0000177TargetHumansTetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sod...
Polypeptides: Sodium channel protein type 10 subunit alphaATP-sensitive inward rectifier potassium channel 10
go.drugbank.com/bio_entities/BE0009591TargetHumansMay be responsible for potassium buffering action of glial cells in the brain (By similarity). Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it (Pu...
Polypeptides: ATP-sensitive inward rectifier potassium channel 10Synonyms: Potassium channel, inwardly rectifying subfamily J member 10Silodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalneck, prostate, and prostatic urethra: the α<sub>1A</sub> subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder
Categories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor AntagonistsProducts: SİLODOPİN 4 MG KAPSÜL, 30 ADET, SİLODOPİN 8 MG KAPSÜL, 30 ADETMitogen-activated protein kinase kinase kinase 10
go.drugbank.com/bio_entities/BE0009462TargetHumansActivates the JUN N-terminal pathway
Polypeptides: Mitogen-activated protein kinase kinase kinase 10Tumor necrosis factor ligand superfamily member 10
go.drugbank.com/bio_entities/BE0010497TargetHumansCytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:10549288, PubMed:26457518). Induces apoptosis. Its activity may be modulated by binding to the d...
Polypeptides: Tumor necrosis factor ligand superfamily member 10Orphenadrine
go.drugbank.com/drugs/DB01173ApprovedInvestigationalA muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Synonyms: N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]ethylamine, N,N-Dimethyl-2-(alpha-2-tolylbenzoyloxy)ethylamineMixtures: Norgesic 35 mg/450 mg Tabletten, MYOGESIC-GProtokylol
go.drugbank.com/drugs/DB06814ApprovedVet approvedProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
Categories: Heterocyclic Compounds, 1-Ring, Epinephrine and similarsProducts: OPTİCAİNE %0.5 GÖZ DAMLASI, ÇÖZELTİ 5 MLCyclopentolate
go.drugbank.com/drugs/DB00979ApprovedA parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Mixtures: Mydriatic-3Categories: Mydriatics and Cycloplegics