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Tryptophan 5-hydroxylase 1
go.drugbank.com/bio_entities/BE0000121TargetEnzymeHumansOxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis
Polypeptides: Tryptophan 5-hydroxylase 1Synonyms: Tryptophan 5-monooxygenase 1Cytosolic purine 5'-nucleotidase
go.drugbank.com/bio_entities/BE0000261TargetEnzymeHumansBroad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705).
Polypeptides: Cytosolic purine 5'-nucleotidaseSynonyms: High Km 5'-nucleotidase, Cytosolic 5'-nucleotidase II5'(3')-deoxyribonucleotidase, mitochondrial
go.drugbank.com/bio_entities/BE0001515TargetHumansDephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879).
Polypeptides: 5'(3')-deoxyribonucleotidase, mitochondrialSynonyms: Deoxy-5'-nucleotidase 2, 5',3'-nucleotidase, mitochondrial5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
go.drugbank.com/bio_entities/BE0001620TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
Polypeptides: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseFunction: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activityOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001677TargetEnzymeEscherichia coli (strain K12)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001956TargetBacillus subtilis (strain 168)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseFunction: orotidine-5'-phosphate decarboxylase activityInosine-5'-monophosphate dehydrogenase
go.drugbank.com/bio_entities/BE0002047TargetStreptococcus pyogenesCatalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays
Polypeptides: Inosine-5'-monophosphate dehydrogenaseLaminin subunit alpha-5
go.drugbank.com/bio_entities/BE0002103TargetHumansBinding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a...
Polypeptides: Laminin subunit alpha-5Synonyms: Laminin-10 subunit alphaSomatostatin receptor type 5
go.drugbank.com/bio_entities/BE0002147TargetHumansReceptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization
Polypeptides: Somatostatin receptor type 5Synonyms: SS-5-RPyrroline-5-carboxylate reductase
go.drugbank.com/bio_entities/BE0002335TargetHumansPolypeptides: Pyrroline-5-carboxylate reductaseFunction: pyrroline-5-carboxylate reductase activity