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Tetrofosmin
go.drugbank.com/drugs/DB11180ApprovedIt presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. … Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788]
Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives ArzneimittelCategories: P-glycoprotein substratesFramycetin
go.drugbank.com/drugs/DB00452ApprovedInvestigationalA component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)
Synonyms: Neomycin B, Fradiomycin BInternational brands: Leukase NSulfadiazine
go.drugbank.com/drugs/DB00359ApprovedInvestigationalVet approvedOne of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Mixtures: TRIMETOMIX 40% powder, ST-480 PowderCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesIlaprazole
go.drugbank.com/drugs/DB11964InvestigationalIlaprazole has been investigated in Helicobacter Infections.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 56 ADET, NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 7 ADETSimvastatin Action Pathway
smpdb.ca/view/SMP0000082Drug actioncontributes to ≤ 20% of its metabolism. … Cytochrome P450 (CYP) enzymes, CYP3A4, CYP3A5, and CYP2C8, have been implicated in this activation step; CYP3A4/5 are responsible for ≥ 80% of simvastatin metabolism while CYP2C8 (not shown in pathway)
Drugs: Cholecalciferol · ATP · Simvastatin · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 moreSpectinomycin
go.drugbank.com/drugs/DB00919ApprovedVet approvedWithdrawnIt is active against gram-negative bacteria and used for the treatment of gonorrhea.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingProducts: TROBICIN FOR INJECTION 2 g/vial, Spectro 5% w/v Oral SolutionPost-essential Thrombocythemia Myelofibrosis (Post-ET MF)
go.drugbank.com/conditions/DBCOND0069581Drugs: RuxolitinibSynonyms: Post ET MF, Post-ET MFSqualene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnIt is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation and provides skin protection. … It is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy.
Mixtures: K-OMEGASQUA (Softgel)Synonyms: (E,E,E,E)-Squalene, (all-E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaeneEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalA prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.
Categories: Prostaglandins ISynonyms: (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidTolbutamide
go.drugbank.com/drugs/DB01124ApprovedIt is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C18 SubstratesSynonyms: 1-Butyl-3-tosylurea, 1-Butyl-3-(p-tolylsulfonyl)urea