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Oxymorphone
go.drugbank.com/drugs/DB01192ApprovedVet approvedIt is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092). … On June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and abuse risks associated with the product's injectable reformulation.
Synonyms: 14-Hydroxydihydromorphinone, (14S)-14-HydroxydihydromorphinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesApraclonidine
go.drugbank.com/drugs/DB00964ApprovedInvestigationalApraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Synonyms: 4-AminoclonidineCategories: Adrenergic alpha-2 Receptor Agonists, Heterocyclic Compounds, 1-RingCocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalIt also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl esterGliquidone
go.drugbank.com/drugs/DB01251ApprovedGliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: GLURENOR 30 MG TABLETTEN, Glurenorm 30 mg - TablettenAcylcarnitine 10-Hydroxydodec-5-enedioylcarnitine
smpdb.ca/view/SMP0124031Metabolic10-Hydroxydodec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 10-hydroxydodec-5-enedioyl-CoA reacts with L-carnitine to form 10-hydroxydodec-5-enedioylcarnitine.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Romiplostim
go.drugbank.com/drugs/DB05332ApprovedInvestigationalFDA approved on August 22, 2008. … Each domain consists of 14 amino acids. Interestingly, romiplostim's amino acid sequence is not similar to that of endogenous thrombopoietin.
Products: NPLATE 250 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET, NPLATE® 250 MCGMesterolone
go.drugbank.com/drugs/DB13587InvestigationalIt is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. … Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT).
Categories: 5-Androstanon (3) DerivativesProducts: PROVIRON 25 MG TABLET, 20 ADET, RESTORE TABLET 25 mgSulfamethizole
go.drugbank.com/drugs/DB00576ApprovedVet approvedA sulfathiazole antibacterial agent.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: S- URISTIX 500 MG CAPSULAS, S*ORIPOL FORTE - SULFAMETIZOL 500 MG CAPSULASPhenprocoumon
go.drugbank.com/drugs/DB00946ApprovedInvestigationalWithdrawnCoumarin derivative that acts as a long-acting oral anticoagulant.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one, 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-oneFramycetin
go.drugbank.com/drugs/DB00452ApprovedInvestigationalA component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)
Synonyms: Neomycin B, Fradiomycin BInternational brands: Leukase N