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Displaying results 3661 - 3670 of 10000 in total
  1. Target

    3',5'-cyclic-AMP phosphodiesterase 4D

    go.drugbank.com/bio_entities/BE0001287
    TargetHumans

    Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes

    Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4DFunction: 3',5'-cyclic-AMP phosphodiesterase activity
  2. Target

    cGMP-dependent 3',5'-cyclic phosphodiesterase

    go.drugbank.com/bio_entities/BE0002085
    TargetHumans

    cGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15938621, PubMed:29392776, PubMed:9210593). Ha...

    Polypeptides: cGMP-dependent 3',5'-cyclic phosphodiesteraseFunction: 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
  3. Target

    tRNA (cytosine(38)-C(5))-methyltransferase

    go.drugbank.com/bio_entities/BE0002517
    TargetHumans

    Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (PubMed:16424344). Has higher activity on tRNA(Asp) modified with queuosine at position 34 (PubMed:30093495)

    Polypeptides: tRNA (cytosine(38)-C(5))-methyltransferaseSynonyms: DNA (cytosine-5)-methyltransferase-like protein 2
  4. Target

    Trafficking protein particle complex subunit 5

    go.drugbank.com/bio_entities/BE0004277
    TargetHumans

    May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Polypeptides: Trafficking protein particle complex subunit 5
  5. Target

    Pregnancy-specific beta-1-glycoprotein 5

    go.drugbank.com/bio_entities/BE0008996
    TargetHumans

    Polypeptides: Pregnancy-specific beta-1-glycoprotein 5Synonyms: PSBG-5, PS-beta-G-5
  6. Target

    Pyridoxal 5'-phosphate synthase subunit Pdx1

    go.drugbank.com/bio_entities/BE0009271
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by Pdx2. … Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

    Polypeptides: Pyridoxal 5'-phosphate synthase subunit Pdx1
  7. Target

    G protein-coupled receptor kinase 5

    go.drugbank.com/bio_entities/BE0013072
    TargetHumans

    Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization,...

    Polypeptides: G protein-coupled receptor kinase 5
  8. Target

    Short transient receptor potential channel 5

    go.drugbank.com/bio_entities/BE0021113
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991). Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with...

    Polypeptides: Short transient receptor potential channel 5Synonyms: hTRP-5, TRP-5
  9. Drug

    Raltitrexed

    go.drugbank.com/drugs/DB00293
    ApprovedInvestigational

    Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.

    Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: TOMUDEX 2 MG FLAKON, 1 ADET, TOMUDEX ® 2 MG
  10. Target

    5-aminolevulinate synthase, non-specific, mitochondrial

    go.drugbank.com/bio_entities/BE0000409
    TargetHumans

    Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products

    Polypeptides: 5-aminolevulinate synthase, non-specific, mitochondrialSynonyms: 5-aminolevulinic acid synthase 1