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3',5'-cyclic-AMP phosphodiesterase 4B
go.drugbank.com/bio_entities/BE0000487TargetHumansHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:15260978). May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to...
Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4BFunction: 3',5'-cyclic-AMP phosphodiesterase activityDelta-1-pyrroline-5-carboxylate synthase
go.drugbank.com/bio_entities/BE0000823TargetHumansBifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine
Polypeptides: Delta-1-pyrroline-5-carboxylate synthase5-aminolevulinate synthase, erythroid-specific, mitochondrial
go.drugbank.com/bio_entities/BE0000898TargetHumansCatalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products (PubMed:14643893, PubMed:21252495, PubMed
Polypeptides: 5-aminolevulinate synthase, erythroid-specific, mitochondrialSynonyms: 5-aminolevulinic acid synthase 23',5'-cyclic-AMP phosphodiesterase 4A
go.drugbank.com/bio_entities/BE0001133TargetHumansHydrolyzes the second messenger 3',5'-cyclic AMP (cAMP), which is a key regulator of many important physiological processes
Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4AFunction: 3',5'-cyclic-AMP phosphodiesterase activity3',5'-cyclic-AMP phosphodiesterase 4C
go.drugbank.com/bio_entities/BE0002353TargetHumansHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes
Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4CFunction: 3',5'-cyclic-AMP phosphodiesterase activityBaculoviral IAP repeat-containing protein 5
go.drugbank.com/bio_entities/BE0003408TargetHumansMultitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:20627126, PubMed:21364656, PubMed:25778398, PubMed:28218735, PubMed:9859993). Component of a chromosome passage protein complex (CP...
Polypeptides: Baculoviral IAP repeat-containing protein 5Serine/threonine-protein kinase PAK 5
go.drugbank.com/bio_entities/BE0009510TargetHumansSerine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor rec...
Polypeptides: Serine/threonine-protein kinase PAK 5Synonyms: PAK-5, p21-activated kinase 5Cinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalCinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Categories: Sex Hormones and Insulins, Calcium-Regulating Hormones and AgentsSynonyms: N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine, (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane aminePivmecillinam
go.drugbank.com/drugs/DB01605ApprovedInvestigationalIt is active against gram-negative organisms and used as for amdinocillin. [PubChem] … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa.
Categories: Heterocyclic Compounds, 2-RingProducts: Selexid 200 mg Filmtabletten, Selexid 400 mg film-coated tabletsTioguanine
go.drugbank.com/drugs/DB00352ApprovedInvestigationalAn antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Categories: Heterocyclic Compounds, 2-Ring, Antineoplastic and Immunomodulating AgentsSynonyms: 2-Aminopurine-6(1H)-thione, 6-TG