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5-aminolevulinate synthase, non-specific, mitochondrial
go.drugbank.com/bio_entities/BE0000409TargetHumansCatalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products
Polypeptides: 5-aminolevulinate synthase, non-specific, mitochondrialSynonyms: 5-aminolevulinic acid synthase 1C-C chemokine receptor type 5
go.drugbank.com/bio_entities/BE0000911TargetHumansReceptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granuloc...
Polypeptides: C-C chemokine receptor type 5Synonyms: CCR-5, CC-CKR-55-phosphohydroxy-L-lysine phospho-lyase
go.drugbank.com/bio_entities/BE0002164TargetHumansCatalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde
Polypeptides: 5-phosphohydroxy-L-lysine phospho-lyaseNeuronal acetylcholine receptor subunit alpha-5
go.drugbank.com/bio_entities/BE0003586TargetHumansComponent of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collecti...
Polypeptides: Neuronal acetylcholine receptor subunit alpha-5Cyclin-dependent kinase 5 activator 1
go.drugbank.com/bio_entities/BE0003819TargetHumansp35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex...
Polypeptides: Cyclin-dependent kinase 5 activator 1Synonyms: Cyclin-dependent kinase 5 regulatory subunit 1Cytochrome b6-f complex subunit 5
go.drugbank.com/bio_entities/BE0003906TargetMastigocladus laminosusComponent of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assemb...
Polypeptides: Cytochrome b6-f complex subunit 5Tartrate-resistant acid phosphatase type 5
go.drugbank.com/bio_entities/BE0004487TargetHumansDephosphorylates a broad range of substrates, including adenosine 5'-diphosphate (ADP), adenosine 5'-triphosphate (ATP), as well as larger phosphoproteins such as osteopontin (SPP1), a highly phosphorylated
Polypeptides: Tartrate-resistant acid phosphatase type 5Synonyms: Type 5 acid phosphataseMAP kinase-activated protein kinase 5
go.drugbank.com/bio_entities/BE0009478TargetHumansTumor suppressor serine/threonine-protein kinase involved in mTORC1 signaling and post-transcriptional regulation. Phosphorylates FOXO3, ERK3/MAPK6, ERK4/MAPK4, HSP27/HSPB1, p53/TP53 and RHEB. Acts as a tumor suppressor by mediating Ras-...
Polypeptides: MAP kinase-activated protein kinase 5Synonyms: MK-5, MAPKAPK-5Solute carrier family 12 member 5
go.drugbank.com/bio_entities/BE0009674TransporterMouseMediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (By similarity). As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required f...
Polypeptides: Solute carrier family 12 member 5Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
go.drugbank.com/bio_entities/BE0010803TargetHumansPhosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating … Also, is able to hydrolyze the 5-phosphate of phosphatidylinositol-4,5-bisphosphate (PtdIns(4,5)P3), 1D-myo-inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate (PubMed:10764818, PubMed:
Polypeptides: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1Synonyms: Inositol polyphosphate-5-phosphatase D, Inositol polyphosphate-5-phosphatase of 145 kDa