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1-phosphatidylinositol 3-phosphate 5-kinase
go.drugbank.com/bio_entities/BE0021269TargetHumansAlso catalyzes the phosphorylation of phosphatidylinositol on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 5-phosphate (PtdIns(5)P) (PubMed:22621786). … Autophosphorylation inhibits its own phosphatidylinositol 3-phosphate 5-kinase activity, stimulates FIG4 lipid phosphatase activity and down-regulates lipid product formation (PubMed:33098764).
Polypeptides: 1-phosphatidylinositol 3-phosphate 5-kinaseSynonyms: Phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase type IIIPyrroline-5-carboxylate reductase 1, mitochondrial
go.drugbank.com/bio_entities/BE0000225TargetHumansOxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H (PubMed:16730026, PubMed:19648921, PubMed:23024808
Polypeptides: Pyrroline-5-carboxylate reductase 1, mitochondrial3',5'-cyclic-AMP phosphodiesterase 4D
go.drugbank.com/bio_entities/BE0001287TargetHumansHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes
Polypeptides: 3',5'-cyclic-AMP phosphodiesterase 4DFunction: 3',5'-cyclic-AMP phosphodiesterase activitycGMP-dependent 3',5'-cyclic phosphodiesterase
go.drugbank.com/bio_entities/BE0002085TargetHumanscGMP-activated cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15938621, PubMed:29392776, PubMed:9210593). Ha...
Polypeptides: cGMP-dependent 3',5'-cyclic phosphodiesteraseFunction: 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activitytRNA (cytosine(38)-C(5))-methyltransferase
go.drugbank.com/bio_entities/BE0002517TargetHumansSpecifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (PubMed:16424344). Has higher activity on tRNA(Asp) modified with queuosine at position 34 (PubMed:30093495)
Polypeptides: tRNA (cytosine(38)-C(5))-methyltransferaseSynonyms: DNA (cytosine-5)-methyltransferase-like protein 2Trafficking protein particle complex subunit 5
go.drugbank.com/bio_entities/BE0004277TargetHumansMay play a role in vesicular transport from endoplasmic reticulum to Golgi
Polypeptides: Trafficking protein particle complex subunit 5Pregnancy-specific beta-1-glycoprotein 5
go.drugbank.com/bio_entities/BE0008996TargetHumansPolypeptides: Pregnancy-specific beta-1-glycoprotein 5Synonyms: PSBG-5, PS-beta-G-5Pyridoxal 5'-phosphate synthase subunit Pdx1
go.drugbank.com/bio_entities/BE0009271TargetPlasmodium falciparum (isolate 3D7)Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by Pdx2. … Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
Polypeptides: Pyridoxal 5'-phosphate synthase subunit Pdx1G protein-coupled receptor kinase 5
go.drugbank.com/bio_entities/BE0013072TargetHumansSerine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization,...
Polypeptides: G protein-coupled receptor kinase 5Short transient receptor potential channel 5
go.drugbank.com/bio_entities/BE0021113TargetHumansForms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991). Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with...
Polypeptides: Short transient receptor potential channel 5Synonyms: hTRP-5, TRP-5