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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
go.drugbank.com/bio_entities/BE0000213TargetHumansRequired for proper complex I assembly (PubMed:30245030). Complex I functions in the transfer of electrons from NADH to the respiratory chain. … Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis.
Synonyms: Complex I-B14NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
go.drugbank.com/bio_entities/BE0000596TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B22Proteasome subunit alpha type-5
go.drugbank.com/bio_entities/BE0003914TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex zeta chainMethylphenobarbital
go.drugbank.com/drugs/DB00849ApprovedA barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Gestonorone
go.drugbank.com/drugs/DB13230ExperimentalGestonorone is often mistaken for gestonorone capproate which has a different chemical structure.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemVimseltinib
go.drugbank.com/drugs/DB17520ApprovedInvestigationalVimseltinib is a small molecule kinase inhibitor targeting colony-stimulating factor 1 receptor (CSF1R). … [L52230] It is highly selective, with a >500-fold selectivity for CSF1R over its nearest off-target kinase.
Proteasome subunit alpha
go.drugbank.com/bio_entities/BE0003353TargetMycobacterium tuberculosisComponent of the proteasome core, a large protease complex with broad specificity involved in protein degradation. … In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin-like protein (Pup).
Synonyms: Proteasome core protein PrcAProteasome subunit beta
go.drugbank.com/bio_entities/BE0004188TargetMycobacterium tuberculosisComponent of the proteasome core, a large protease complex with broad specificity involved in protein degradation. … In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin-like protein (Pup).
Synonyms: Proteasome core protein PrcBDaclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnDespite being approved for use, Zinbryta (daclizumab)'s complex pre-existing safety profile consisting of its restricted availability through a Risk Evaluation and Mitigation Strategy program [L1738] and … Regardless of the withdrawal of Zenapax, Biogen and Abbvie's Zinbryta (daclizumab), as indicated for the treatment of adult patients with relapsing forms of multiple sclerosis, was approved for use by
Sebetralstat
go.drugbank.com/drugs/DB18305ApprovedInvestigationalSebetralstat is the first and only oral on-demand treatment for HAE, providing a convenient alternative to injectable therapies that have been challenging for patients to use [L53538, A274293]. … The U.S. Food and Drug Administration approved sebetralstat on July 7, 2025, for treating acute HAE attacks in patients aged 12 years and older [L53533, L53538].