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Acylcarnitine Undec-5-enedioylcarnitine
smpdb.ca/view/SMP0123965MetabolicUndec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, undec-5-enedioyl-CoA reacts with L-carnitine to form undec-5-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Atogepant
go.drugbank.com/drugs/DB16098ApprovedInvestigational[A239094] The "gepants" family of drugs, including atogepant, are comparatively well-tolerated[A189207,L38739] and may provide a desirable treatment option for patients struggling with adverse reactions … [L38814] In December 2022, atogepant received Health Canada approval for the prevention of episodic migraine in adults.
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesProducts: AQUIPTA® 60 MG, AQUIPTA® 10 MGPhosphatidylethanolamine Biosynthesis PE(16:0/20:5(6E,8Z,11Z,14Z,17Z)-OH(5))
smpdb.ca/view/SMP0127207MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...
Phosphatidylethanolamine Biosynthesis PE(20:5(6E,8Z,11Z,14Z,17Z)-OH(5)/15:0)
smpdb.ca/view/SMP0127519MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...
Chlorprothixene
go.drugbank.com/drugs/DB01239ApprovedInvestigationalWithdrawnChlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. … Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: Truxal 50 mg - Filmtabletten, Truxal 15 mg - FilmtablettenTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigational[A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Synonyms: 2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid, 6-BENZOXAZOLECARBOXYLIC ACID, 2-(3,5-DICHLOROPHENYL)-Categories: Heterocyclic Compounds, 2-RingDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnA synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexene, α,α'-diethyl-(E)-4,4'-stilbenediolMefloquine
go.drugbank.com/drugs/DB00358ApprovedIndividuals at the highest risk for malaria are those in disease naïve populations, children under age 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women … Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world.
Synonyms: [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol, 4-QUINOLINEMETHANOL, .ALPHA.-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (R*,S*)-(±)-Mixtures: อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 25/55 มก.Zotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawn[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.[A31857] Zotepine was never approved by the FDA. … In 1993, it was classified as inactive drug substance (Status I, Type II) and in 1995 the FDA studied the manufacturing procedures of Zotepine tablets in Germany, but the status remained inactive.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: ZOLEPTIL © 50 MG TABLETAS RECUBIERTAS.Benperidol
go.drugbank.com/drugs/DB12867ApprovedWithdrawnBenperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Products: BENPERIDOL-NEURAX 2 MG, BENPERIDOL-NEURAX 4 MG