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Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
go.drugbank.com/bio_entities/BE0014411TargetHumansAlso has 3'->5' exonuclease activity towards double-stranded (ds)DNA with a 5'-overhang (PubMed:11863428). … Unwinds some G-quadruplex DNA (d(CGG)n tracts); unwinding seems to occur in both 5'-3' and 3'-5' direction and requires a short single-stranded tail (PubMed:10212265). d(CGG)n tracts have a propensity
Polypeptides: Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNFunction: 3'-5' DNA helicase activityMenatetrenone
go.drugbank.com/drugs/DB12148InvestigationalMenatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
Categories: Vitamin KProducts: GLAKAY ( 15 MG ), GLAKAY (15 MG.)Zinc chloride
go.drugbank.com/drugs/DB14533ApprovedZinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes.
Mixtures: AMINOMIX 1 NOVUM 1500 ML, AMINOMIX 2 NOVUM 1500 MLCategories: Compounds used in a research, industrial, or household settingCholine alfoscerate
go.drugbank.com/drugs/DB04660InvestigationalA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids.
Synonyms: sn-3-GPC, glycerol-3-phosphocholineProducts: MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADETDirithromycin
go.drugbank.com/drugs/DB00954InvestigationalDirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Synonyms: (9S)-9-deoxo-11-deoxy-9,11-(imino((1R)-2-(2-methoxyethoxy)ethylidene)oxy)erythromycinCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsHydrocortisone butyrate
go.drugbank.com/drugs/DB14540ApprovedVet approvedSynonyms: H-17-B, 17-O-butyrylcortisolCategories: 17-Hydroxycorticosteroids, Cytochrome P-450 Substrates5'-AMP-activated protein kinase subunit beta-1
go.drugbank.com/bio_entities/BE0000254TargetHumansNon-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-pro...
Polypeptides: 5'-AMP-activated protein kinase subunit beta-1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
go.drugbank.com/bio_entities/BE0000473TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...
Polypeptides: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 53-oxo-5-alpha-steroid 4-dehydrogenase 2
go.drugbank.com/bio_entities/BE0000585TargetEnzymeHumansCatalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms (PubMed … Converts testosterone into 5-alpha-dihydrotestosterone (DHT), the most active androgen in the prostate, as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a
Polypeptides: 3-oxo-5-alpha-steroid 4-dehydrogenase 2Synonyms: 5 alpha-SR2, Type II 5-alpha reductaseA disintegrin and metalloproteinase with thrombospondin motifs 5
go.drugbank.com/bio_entities/BE0003730TargetHumansMetalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chon...
Polypeptides: A disintegrin and metalloproteinase with thrombospondin motifs 5Synonyms: ADAMTS-5, ADAM-TS 5