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Crotamiton
go.drugbank.com/drugs/DB00265ApprovedCrotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. … It is miscible with alcohol and with methanol.
Categories: Compounds used in a research, industrial, or household settingProducts: CROTAMITON CREAM 10% v/w, CROTOCORT CREAM 10% W/WPropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: LUBTANE %0,4 + %0,3 LUBRİKANT GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, 10 ML, SKINOREN %20 KREM, 30 GCategories: Compounds used in a research, industrial, or household settingBrentuximab vedotin
go.drugbank.com/drugs/DB08870ApprovedInvestigational[L1737] The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy regimen compared to the previous standard of care. … Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE).
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: Monoclonal antibody SGN-30, Moab, chimeric, SGN-30, to CD30 antigenDeucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigationalUnlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity … [L43150] It was later approved by Health Canada in November 2022 [L44216] and by the European Medicines Agency in March 2023.[L45788]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: SOTYKTU 6 mg film coated tablets, SOTYKTU® 6MG TABLETAS RECUBIERTASProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1
go.drugbank.com/bio_entities/BE0000087TargetHumansPart of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine r...
Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1Gamma-aminobutyric acid receptor subunit alpha-5
go.drugbank.com/bio_entities/BE0000471TargetHumansExtrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … GABAARs containing alpha-5/GABRA5 subunits are mainly extrasynaptic and contribute to the tonic GABAergic inhibition in the hippocampus (By similarity).
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABAAR subunit alpha-5, GABA(A) receptor subunit alpha-51-deoxy-D-xylulose 5-phosphate reductoisomerase
go.drugbank.com/bio_entities/BE0001575TargetEscherichia coli (strain K12)Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
Polypeptides: 1-deoxy-D-xylulose 5-phosphate reductoisomeraseSynonyms: 1-deoxyxylulose-5-phosphate reductoisomeraseProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2
go.drugbank.com/bio_entities/BE0002192TargetHumansForms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links
Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2T cell receptor beta variable 6-5
go.drugbank.com/bio_entities/BE0021562TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...
Polypeptides: T cell receptor beta variable 6-5Ilaprazole
go.drugbank.com/drugs/DB11964InvestigationalIlaprazole has been investigated in Helicobacter Infections.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 56 ADET, NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 7 ADET