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Displaying results 3841 - 3850 of 10000 in total
  1. Drug

    2,2'-Dibenzothiazyl disulfide

    go.drugbank.com/drugs/DB14201
    Approved

    2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer.

  2. Drug

    ISS-1018

    go.drugbank.com/drugs/DB05463
    Investigational

    ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha … (TNF-alpha) by plasmacytoid dendritic cells (pDC).

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  3. Indication

    Allergic Diseases

    go.drugbank.com/conditions/DBCOND0110864
    Drugs: Acetaminophen · Ammonium chloride · Betamethasone phosphate · Brompheniramine · Buclizine · Budesonide +17 more
    Synonyms: Other and unspecified allergy, Atopic AND/OR hypersensitivity state
  4. Drug

    Imlifidase

    go.drugbank.com/drugs/DB15258
    ApprovedInvestigational

    [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies. … [A225836] As a result, highly sensitized individuals experience marked delays on transplant lists due to the challenges associated with procuring an HLA compatible donor graft.

    Categories: Antineoplastic and Immunomodulating Agents
  5. Drug

    Periciazine

    go.drugbank.com/drugs/DB01608
    Approved

    It is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing hostility, impulsiveness and aggressiveness. … It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine effects and an action on the extrapyramidal system.

  6. Drug

    Viomycin

    go.drugbank.com/drugs/DB06827
    Approved

    These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomycin was derived from the actinomycete _Streptomyces puniceus_. … Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin.

    Categories: Amino Acids, Peptides, and Proteins
  7. Target

    Zinc transporter ZIP2

    go.drugbank.com/bio_entities/BE0009889
    TransporterHumans

    The Zn(2+) uniporter activity is independent of H(+)-driving force, but is modulated by extracellular pH and membrane potential. … In the skin, aids in the differentiation of keratinocytes in the epidermis (By similarity)

    Synonyms: Zrt- and Irt-like protein 2
  8. Indication

    Neurological Manifestations

    go.drugbank.com/conditions/DBCOND0031286
    Drugs: Cytidine · Elivaldogene autotemcel · Uridine
    Synonyms: Neurologic Signs and Symptoms, Neurological signs and symptoms NEC
  9. Drug

    Levocabastine

    go.drugbank.com/drugs/DB01106
    Approved

    Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.

    Categories: Decongestants and Antiallergics
  10. Drug

    Methscopolamine

    go.drugbank.com/drugs/DB11315
    Approved

    The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective in decreasing the rate of recurrence of peptic ulcers as well as preventing complications. … Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors.

    Mixtures: Allergy DN II, Allergy DN IICategories: Alimentary Tract and Metabolism, Mydriatics and Cycloplegics