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Displaying results 3841 - 3850 of 10000 in total
  1. Drug

    N-Acetylmethionine

    go.drugbank.com/drugs/DB01646
    Investigational

    Mixtures: AZONEFROL-PD PERİTON DİYALİZ ÇÖZELTİSİ, 2000 ML TEKLİ TORBA, AZONEFROL-PD PERİTON DİYALİZ ÇÖZELTİSİ, 2500 ML ÇİFTLİ TORBASynonyms: (2S)-2-acetamido-4-(methylsulfanyl)butanoic acid, N-Ac-Met
  2. Drug

    Mapatumumab

    go.drugbank.com/drugs/DB18945
    Investigational

    Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).

    Synonyms: Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal trm-1 .lambda.-chain, dimer, Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy chain), disulphide with human monoclonal trm-1 .lambda.-chain, dimer
  3. Drug

    Vilastobart

    go.drugbank.com/drugs/DB19327
    Investigational

    Vilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).

    Synonyms: immunoglobulin G1-fused prodomain kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody, G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-
  4. Drug

    DSP-5336

    go.drugbank.com/drugs/DB18514
    Investigational

    DSP-5336 is a menin inhibitor.

    Synonyms: BENZAMIDE, 5-FLUORO-2-((4-(7-(((1S,3S,4R)-5-METHYLENE-2-AZABICYCLO(2.2.2)OCT-3-YL)CARBONYL)-2,7-DIAZASPIRO(3.5)NON-2-YL)-5-PYRIMIDINYL)OXY)-N,N-BIS(1-METHYLETHYL)-
  5. Drug

    (2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol

    go.drugbank.com/drugs/DB04776
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Aftin-4, (2R)-2-({6-[Benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-1-butanol
  6. Drug

    Silodosin

    go.drugbank.com/drugs/DB06207
    ApprovedInvestigational

    a negative impact on the quality of life of patients. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder

    Categories: Drugs Used in Benign Prostatic Hypertrophy, Cytochrome P-450 SubstratesProducts: SILODOSINA EG, SILODOSIN AL 4 MG HKP
  7. Pathway

    Acylcarnitine (5Z)-7-[(1R)-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123464
    Metabolic

    Once inside the cell it undergoes a reaction to form an acyl-CoA derivative called (5Z)-7-[(1R)-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-2-en-1-yl]hept-5-enoyl-CoA. … This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  8. Drug

    Calmangafodipir

    go.drugbank.com/drugs/DB18398
    Investigational

    Synonyms: Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine) manganese complexes trisodium trihydrogen manganate, Calmangafodipir (ca4mn(dpdp)5)Categories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  9. Pathway

    Acylcarnitine (5Z)-7-{2-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123542
    Metabolic

    Once inside the cell it undergoes a reaction to form an acyl-CoA derivative called (5Z)-7-{2-[(1E,3R)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopent-1-en-1-yl}hept-5-enoyl-CoA. … This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  10. Drug

    Atropine

    go.drugbank.com/drugs/DB00572
    ApprovedInvestigationalVet approved

    Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active. … [A251660] Atropine is a relatively inexpensive drug and is included in the World Health Organization List of Essential Medicines.[A251675]

    Mixtures: LOMOTİL 2,5 MG + 0,025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML, PHARMANIAGA DIPHENOXYLATE A TABLETCategories: P-glycoprotein substrates