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Displaying results 3981 - 3990 of 10000 in total
  1. Drug

    OBI-3424

    go.drugbank.com/drugs/DB16057
    Investigational

    OBI-3424 is under investigation in clinical trial NCT04315324 (Study to Test Akr1c3-activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/refractory T-cell Acute Lymphoblastic Leukemia (T-ALL

    Synonyms: Phosphinic acid, P,P-bis(1-aziridinyl)-, (1R)-1-(3-(3-((dimethylamino)carbonyl)phenoxy)-4-nitrophenyl)ethyl ester, 3-(5-((1R)-1-(Bis(aziridin-1-yl(phosphoryloxy)ethyl)-2-nitrophenoxy)-N,N-dimethylbenzamide
  2. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).

    Synonyms: [2-(2,6-dichloroanilino)phenyl]acetic acid, 2-((2,6-dichlorophenyl)amino)benzeneacetic acidMixtures: Dfs 1.5%/ms 25%/menth 6%/cap 0.025% Pak, MUSCOFLEX DUO 75 MG/4 MG DEĞIŞTIRILMIŞ SALIMLI TABLET ,TABLET, 14 ADET
  3. Drug

    Niclosamide

    go.drugbank.com/drugs/DB06803
    ApprovedInvestigationalVet approved

    Over 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals. … Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases.

    Mixtures: เค.16 ชนิดเม็ดCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates
  4. Drug

    Barium sulfate

    go.drugbank.com/drugs/DB11150
    Approved

    This drug is used as a contrast agent in diagnostic x-ray procedures. … Barium sulfate occurs in nature as the mineral _barite_. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1957].

    Mixtures: E-Z HD SULFATODE BARIO PARA SUSPENSION, E-Z HD SULFATODE BARIO PARA SUSPENSIONCategories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Activity
  5. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 9-hydroxyrisperidone
  6. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids.

    Mixtures: ROZA %1 + %2 KREM (30 G), UREACORT %0,5 + %5 KREM (30 G)Products: EXCİPİAL LİPO % 4 EMÜLSİYON, 200 ML, UBIT TABLET 100 MG
  7. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion. … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer.

    Mixtures: OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADA, ESOVIP 20/1680 MG TOZ İÇEREN SAŞE, 14 ADETCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  8. Drug

    Benperidol

    go.drugbank.com/drugs/DB12867
    ApprovedWithdrawn

    Benperidol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.

    Products: BENPERIDOL-NEURAX 4 MG, BENPERIDOL-NEURAX 2 MG
  9. Drug

    Dyphylline

    go.drugbank.com/drugs/DB00651
    ApprovedWithdrawn

    Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.

    Mixtures: Dy G, Dilex-G 400Categories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Interferon alfa-2b

    go.drugbank.com/drugs/DB00105
    ApprovedInvestigational

    Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23.

    Synonyms: Interferon alfa 2-b, Intron AMixtures: Intron A, Intron A