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Metabolism and Physiological Effects of Uridine
smpdb.ca/view/SMP0124871MetabolicMore specifically, uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. … L-glutamine is first converted to carbamoyl phosphate then to N-Carbamoyl-L-aspartate and finally to dihydroorotate by the CAD protein (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and
D-Arginine and D-Ornithine Metabolism
smpdb.ca/view/SMP0000036MetabolicD-Amino acids have been show to be present in high concentrations in humans and play a role in biological functions. … DAAO is highly specific towards D-amino acids and favours free neutral D-amino acids or those with hydrophobic, polar or aromatic groups. Acidic amino acids are not catalyze by DAOO.
Metabolism and Physiological Effects of Phenylacetylglutamine
smpdb.ca/view/SMP0123208MetabolicPhenylacetylglutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a common metabolite that occurs naturally in human urine. … Phenylacetylglutamine is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound.
Drugs: Phenylalanine · L-Glutamine · Adenosine phosphate · ATP · Magnesium cation · Phenylpyruvic acid +1 moreMetabolism and Physiological Effects of Phenol
smpdb.ca/view/SMP0123255MetabolicPhenol is shown to cause cardiovascular disease and enhance the production of reactive oxygen species and cause oxidative stress. … Phenol can get further metabolized in a liver hepatocyte to Phenyl sulphate and Phenyl glucuronide. However phenol itself is shown to be a major uremic toxin through high levels of retention.
Metabolism and Physiological Effects of Choline
smpdb.ca/view/SMP0124739MetabolicCholine is obtained from foods like poultry, meat, fish, dairy and eggs. … TMAO has negative effects on organs such as the heart, kidney and vascular system by contributing to cardiovascular disease, atherosclerosis, endothelial dysfunction and kidney disease.
Metabolism and Physiological Effects of Dimethylglycine
smpdb.ca/view/SMP0124873MetabolicThe human body produces DMG when metabolizing choline into glycine. Choline is obtained from dietary sources like meat, fish, eggs and poultry. … Dimethylglycine (DMG) is an amino acid derivative found in the cells of all plants and animals and can be obtained in the diet in small amounts from grains and meat.
Drugs: Choline · Methionine · NADH · Zinc · N,N-dimethylglycine · Flavin adenine dinucleotide +1 moreMetabolism and Physiological Effects of Phenylacetylglycine
smpdb.ca/view/SMP0126858MetabolicThe presence of phenylacetylglycine in urine has been confirmed for dogs, rats and mice. However, the presence of this compound in human urine is controversial. … Phenylacetic acid may arise from exposure to styrene (plastic) or through the consumption of fruits and vegetables.
Drugs: GlycineMetabolism and Physiological Effects of Hippuric Acid
smpdb.ca/view/SMP0123209MetabolicIt can reduce blood clotting and, in the kidney, inhibit organic acid secretion. It is associated with phenylketonuria, propionic acidemia, and tyrosinemia I (genetic metabolic disorders). … After ingestion and absorption in the gut, benzoic acid is transported into the hepatic liver cell from blood where it undergoes two metabolic reactions.
Metabolism and Physiological Effects of Phenyl glucuronide
smpdb.ca/view/SMP0123227MetabolicPhenyl glucuronide is a phenolic compound that is formed through gut microbial metabolism from dietary tyrosine and a glucuronidation reaction in liver hepatic cells.
Metabolism and Physiological Effects of Indoxyl glucuronide
smpdb.ca/view/SMP0123239MetabolicIndoxyl glucuronide is an indole compound that is formed through gut microbial metabolism from dietary tryptophan and a glucuronidation reaction in liver hepatic cells.