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Displaying results 4021 - 4030 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(22:5(7Z,10Z,13Z,16Z,19Z)/22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z)/16:0)

    smpdb.ca/view/SMP0255497
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  2. Drug

    Rufinamide

    go.drugbank.com/drugs/DB06201
    Approved

    Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. … Clinical trials suggest its efficacy in the treatment of partial seizures.

    Categories: Cytochrome P-450 CYP3A Inducers, Heterocyclic Compounds, 1-RingProducts: INOVELON® 400 MG, INOVELON FILM-COATED TABLET 200 MG
  3. Drug

    Pranoprofen

    go.drugbank.com/drugs/DB13514
    Investigational

    Pranoprofen is an anti-inflammatory agent.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingProducts: OFTALAR STERIL GOZ DAMLASI 5 ML
  4. Drug

    Reboxetine

    go.drugbank.com/drugs/DB00234
    ApprovedInvestigationalWithdrawn

    Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. … Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Edronax 4 mg - Tabletten, EDRONAX 4 MG TABLET, 60 ADET
  5. Pathway

    Ribose-5-phosphate Isomerase Deficiency

    smpdb.ca/view/SMP0000519
    Disease

    It reversibly converts D-ribulose 5-phosphate into D-ribose 5-phosphate. … Ribose-5-phosphate isomerase (RPI) deficiency, is a genetic disorder caused by mutations in the RPIA gene that codes for RPI.

    Drugs: Adenosine phosphate · ATP · Magnesium cation · Iron · 5-O-phosphono-alpha-D-ribofuranosyl diphosphate · D-glyceraldehyde 3-phosphate +4 more
    Enzymes: Ribose-5-phosphate isomerase
  6. Pathway

    Acylcarnitine 2-Hydroxy-5-octenoylcarnitine

    smpdb.ca/view/SMP0123373
    Metabolic

    2-Hydroxy-5-octenoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 2-hydroxy-5-octenoyl-CoA reacts with L-carnitine to form 2-hydroxy-5-octenoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  7. Pathway

    Acylcarnitine 6-hydroxynon-5-enoylcarnitine

    smpdb.ca/view/SMP0123424
    Metabolic

    6-hydroxynon-5-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 6-hydroxynon-5-enoyl-CoA reacts with L-carnitine to form 6-hydroxynon-5-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  8. Pathway

    Acylcarnitine 5-Hydroxydec-3-enoylcarnitine

    smpdb.ca/view/SMP0123867
    Metabolic

    5-Hydroxydec-3-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-3-enoyl-CoA reacts with L-carnitine to form 5-hydroxydec-3-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  9. Pathway

    Acylcarnitine 5-Hydroxydec-6-enoylcarnitine

    smpdb.ca/view/SMP0123870
    Metabolic

    5-Hydroxydec-6-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-hydroxydec-6-enoyl-CoA reacts with L-carnitine to form 5-hydroxydec-6-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  10. Pathway

    Acylcarnitine 2-Hydroxyundec-5-enoylcarnitine

    smpdb.ca/view/SMP0123960
    Metabolic

    2-Hydroxyundec-5-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 2-hydroxyundec-5-enoyl-CoA reacts with L-carnitine to form 2-hydroxyundec-5-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5