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Displaying results 4051 - 4060 of 10000 in total
  1. Drug

    Baloxavir marboxil

    go.drugbank.com/drugs/DB13997
    ApprovedInvestigational

    [A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: XOFLUZA 20 MG FİLM KAPLI TABLET, 4 ADET, XOFLUZA 40 MG FİLM KAPLI TABLET, 1 ADET
  2. Target

    Arylsulfatase A

    go.drugbank.com/bio_entities/BE0003195
    TargetEnzymeHumans

    Lysosomal enzyme that catalyzes the hydrolysis of cerebroside-3-sulfate (N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine) into cerebroside and sulfate, a reaction that requires the activator protein … Also involved in the catabolism of other sulfoglycosphingolipids such as SB1a and SM3 (beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) (By similarity)

    Polypeptides: Arylsulfatase A
  3. Target

    Bontoxilysin-A

    go.drugbank.com/bio_entities/BE0004102
    TargetClostridium botulinum

    Polypeptides: Bontoxilysin-ASynonyms: A, boNT/A
  4. Target

    Filamin-A

    go.drugbank.com/bio_entities/BE0009099
    TargetHumans

    Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. … Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs.

    Polypeptides: Filamin-ASynonyms: FLN-A
  5. Target

    Toxin A

    go.drugbank.com/bio_entities/BE0010938
    TargetPeptoclostridium difficile

    Toxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains

    Polypeptides: Toxin A
  6. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant. … A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables.

    Mixtures: Collag-EN, Calcium With Mg Zn Mn Cu CR Si and Vit. C & DCategories: Compounds used in a research, industrial, or household setting, ascorbic acid (vit C)
  7. Drug

    Pimozide

    go.drugbank.com/drugs/DB01100
    Approved

    A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: พีไซด์ 4, NOROFREN 2 MG TABLET, 10 ADET
  8. Drug

    IDN-7314

    go.drugbank.com/drugs/DB18073
    Experimental

    Synonyms: (s)-3-((s)-2-(2-((2,6-difluorophenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid, L-alaninamide, n-(2,6-difluorophenyl)-2-oxoglycyl-n-((1s)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl)-
  9. Indication

    Severe Hemophilia A

    go.drugbank.com/conditions/DBCOND0034640
    Drugs: Valoctocogene roxaparvovec
    Synonyms: Hemophilia A, Severe, Severe Hemophilia A
  10. Indication

    Stage 4 gastrointestinal adenocarcinoma

    go.drugbank.com/conditions/DBCOND0020929
    Drugs: Floxuridine
    Synonyms: Stage 4 gastrointestinal adenocarcinoma