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Displaying results 4051 - 4060 of 10000 in total
  1. Drug

    Ganirelix

    go.drugbank.com/drugs/DB06785
    ApprovedInvestigational

    Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999.

    Products: NOVOLEX 0.25 MG/0.5 ML SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, ORGALUTRAN® 0.25 MG / 0.5 ML SOLUCION INYECTABLE
  2. Drug

    Folitixorin

    go.drugbank.com/drugs/DB17113
    Experimental

    Synonyms: L-glutamic acid, n-(4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo(1,5-f)pteridin-8(9h)-yl)benzoyl)-Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Lorazepam

    go.drugbank.com/drugs/DB00186
    ApprovedInvestigational

    Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.

    Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: Lorazepam Macure 4 mg/ml Injektionslösung, LORAZEPAM EG
  4. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. … Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A1 SubstratesProducts: Fluvastatin Sandoz 40 mg - Hartkapseln, FLUVASTATINA EG
  5. Drug

    Trabectedin

    go.drugbank.com/drugs/DB05109
    ApprovedInvestigational

    Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically. … Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery.

    Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: Trabectedin TEVA 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Trabectedin SUN 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  6. Drug

    Erenumab

    go.drugbank.com/drugs/DB14039
    ApprovedInvestigational

    Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … CGRP receptor, which is believed to play a critical role in migraine [L2823].

    Products: Pasurta 70mg/ml Solution for Injection in a Prefilled Syringe, PASURTA® 140 MG /ML
  7. Drug

    Glycerin

    go.drugbank.com/drugs/DB09462
    ApprovedInvestigational

    A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

    Mixtures: Cellmov Cell Line Mask, Essential Solution Vita A Mask SheetCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP2E1 Inducers
  8. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300] … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.

    Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, Dyrax-Q TabSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
  9. Drug

    Efocipegtrutide

    go.drugbank.com/drugs/DB18194
    Investigational

    Efocipegtrutide is a long-acting, monomeric peptide triple agonist.

    Synonyms: IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)-L-PROLINE), 1-ETHER WITH .ALPHA.-(3-((3-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOPROPYL)AMINO)PROPYL, HM15211 (LONG-ACTING GLP-1/GIP/GLUCAGON TRIPLE AGONIST)
  10. Drug

    Petrolatum

    go.drugbank.com/drugs/DB11058
    ApprovedInvestigational

    A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

    Mixtures: Dg Baby Vitamins A and D, Veradex-ECategories: Compounds used in a research, industrial, or household setting