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Displaying results 4111 - 4120 of 10000 in total
  1. Drug

    Bupivacaine

    go.drugbank.com/drugs/DB00297
    ApprovedInvestigational

    Bupivacaine is a widely used local anesthetic agent.

    Mixtures: BUVACAINA® PESADA SOLUCION INYECTABLE 20 MG/ 4 ML, Physicians EZ Use M-predCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family. … [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties.

    Mixtures: UR N-C Urinary Antiseptic, Me NaPhos MB Hyo 1Synonyms: [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (S)-atropine
  3. Indication

    Acute Hepatitis C Genotype 4

    go.drugbank.com/conditions/DBCOND0173312
    Drugs: Glecaprevir · Pibrentasvir
    Synonyms: Genotype 4 Acute Hepatitis C, Acute Hepatitis C Genotype 4
  4. Indication

    Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089512
    Drugs: Anti-inhibitor coagulant complex · Coagulation factor VIIa Recombinant Human · Emicizumab · Fitusiran · Moroctocog alfa · Rurioctocog alfa pegol +2 more
    Synonyms: Bleeding caused by Hemophilia A
  5. Indication

    Genotype 4 Chronic Hepatitis C

    go.drugbank.com/conditions/DBCOND0074476
    Drugs: Asunaprevir · Elbasvir · Glecaprevir · Grazoprevir · Ledipasvir · Pibrentasvir +3 more
    Synonyms: Chronic hepatitis C genotype 4, Hepatitis C virus genotype 4
  6. Indication

    Stage 4 Chronic Kidney Disease

    go.drugbank.com/conditions/DBCOND0073091
    Drugs: Finerenone
    Synonyms: CKD Stage 4, Chronic Kidney Disease Stage 4
  7. Drug

    Bleximenib

    go.drugbank.com/drugs/DB19328
    Investigational

    Bleximenib is under investigation in clinical trials NCT04811560 (A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia) and NCT05453903 (A Study of Bleximenib in Combination With Acute Myeloid

    Synonyms: Benzamide, N-ethyl-5-fluoro-2-[[5-[2-[(1R)-4-[(2-methoxyethyl)methylamino]-1-(1-methylethyl)butyl]-2,6-diazaspiro[3.4]oct-6-yl]-1,2,4-triazin-6-yl]oxy]-N-(1-methylethyl)-, N-ethyl-5-fluoro-2-{[5-(2-{(3R)-6-[(2-methoxyethyl)(methyl)amino]-2-methylhexan-3-yl}-2,6-diazaspiro[3.4]octan-6-yl)-1,2,4-triazin-6-yl]oxy}-N-(propan-2-yl)benzamide
  8. Indication

    Influenza A Virus Infection

    go.drugbank.com/conditions/DBCOND0036858
    Drugs: Amantadine · Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen · Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) · Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen · Influenza A virus A/New caledonia/71/2014 (H3N2) live (attenuated) antigen · Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) +3 more
    Synonyms: Influenza A, Influenza A H1N1
  9. Indication

    Influenza A, Influenza B

    go.drugbank.com/conditions/DBCOND0051432
    Drugs: Oseltamivir
    Synonyms: Influenza A,B, Influenza A, Influenza B
  10. Pathway

    Acylcarnitine (4Z,7Z,10S,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine

    smpdb.ca/view/SMP0123478
    Metabolic

    Once inside the cell it undergoes a reaction to form an acyl-CoA derivative called (4Z,7Z,10S,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoyl-CoA … This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more