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ZEN-012

It is developed for the treatment of solid tumors. … ZEN-012 is a novel small molecule and the first anti-cancer drug in development involving two mechanisms of action: tubulin and topoisomerase II inhibition.

Citrulline

It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.

Eragidomide

Eragidomide is under investigation in clinical trial NCT04297124 (A Study to Evaluate the Metabolism and Excretion of [14C]-CC-90009 in Healthy Male Subjects).

Chlorzoxazone

It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

Metergoline

[A27181] Its use has been studied in various clinical settings such as a treatment for seasonal affective disorder, prolactin hormone regulation due to its inhibitory effect on prolactin release,[A27182 … Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors.

Brompheniramine

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.

Aluminium phosphate

Olokizumab

Targeting IL-6 function can be achieved directly, or through interrupting the IL-6 receptor or gp130 receptor axes.

Etamivan

Etamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.