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Displaying results 4131 - 4140 of 10000 in total
  1. Pathway

    Acylcarnitine 6-hydroxynon-4-enoylcarnitine

    smpdb.ca/view/SMP0123423
    Metabolic

    6-hydroxynon-4-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 6-hydroxynon-4-enoyl-CoA reacts with L-carnitine to form 6-hydroxynon-4-enoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Pathway

    Acylcarnitine 4-Hydroxy-6-octenoylcarnitine

    smpdb.ca/view/SMP0123374
    Metabolic

    4-Hydroxy-6-octenoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 4-hydroxy-6-octenoyl-CoA reacts with L-carnitine to form 4-hydroxy-6-octenoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Drug

    Tavolixizumab

    go.drugbank.com/drugs/DB15042
    Investigational

    Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENSTNFRSF4 (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 4, OX40, CD134)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-451) (CHIMERIC, VH (MUS MUSCULUS IGHV3-8*02 -(IGHD)-HOMO SAPIEN
  4. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

    Synonyms: 3-pyridinecarboxamide, β-pyridinecarboxamideMixtures: B Plus C 300 mg, ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL
  5. Drug

    Octreotide

    go.drugbank.com/drugs/DB00104
    ApprovedInvestigational

    Acromegaly is a life-threatening disease requiring life-long management. … Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP3A InhibitorsProducts: SANDOSTATIN VIALES PARA DOSIS MULTIPLE 1 MG/ 5 ML, SANDOSTATIN® LAR® 30 MG MICROESFERAS PARA INYECCION
  6. Target

    N-acetylgalactosamine-6-sulfatase

    go.drugbank.com/bio_entities/BE0000883
    EnzymeTargetHumans

    Lysosomal enzyme that hydrolyzes sulfate groups from glycosaminoglycans (GAGs), keratan sulfate (KS) and chondroitin-6-sulfate (C6S)

    Polypeptides: N-acetylgalactosamine-6-sulfataseSynonyms: Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfate sulfatase
  7. Target

    Trehalose-6-phosphate synthase

    go.drugbank.com/bio_entities/BE0001334
    TargetEscherichia coli (strain K12)

    Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.

    Polypeptides: Trehalose-6-phosphate synthaseSynonyms: Trehalose-6-phosphate synthase
  8. Target

    Cyclin-dependent kinase 6

    go.drugbank.com/bio_entities/BE0002212
    TargetHumans

    Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase a...

    Polypeptides: Cyclin-dependent kinase 6Synonyms: Cell division protein kinase 6
  9. Target

    Acyl-CoA 6-desaturase

    go.drugbank.com/bio_entities/BE0002246
    TargetEnzymeHumans

    Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleate (GLA) (18:3n-6) and stearidonate (18:4n-3), respectively (PubMed … , acting as a fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 6 of the fatty acyl chain.

    Polypeptides: Acyl-CoA 6-desaturaseSynonyms: Delta-6 desaturase, Delta(6) desaturase
  10. Target

    Aac(6')-Ii protein

    go.drugbank.com/bio_entities/BE0002686
    TargetEnzymeEnterococcus faecium

    Polypeptides: Aac(6')-Ii protein